Dr. Martin Picard
๐ค SpeakerAppearances Over Time
Podcast Appearances
Correct.
Okay.
And there were a few papers a few years ago that said, oh, no, look here.
There's this one case.
This one kid or these two kids that have paternal father mitochondria.
Turns out it was like a mistake in the sequencing.
So mothers are truly always right.
I don't know of studies that have asked that question about like subjective energy or like the energy to do stuff and which we can, I think we'll talk more about, but people have looked at other more tractable, which what we do in biomedicine, we take things that we can measure objectively or like, you know, run on the gel or sequence or, you know, objectify with a biomarker in the clinic.
People have looked at longevity, right?
Are you more likely to live long if your mom lived long or if your dad lived long?
Turns out the heritability of longevity is more maternal than paternal.
Are you more likely to have a mental health disorder or to have Parkinson's or Alzheimer's if your mom or your dad had it?
Some evidence say it's more maternally inherited than paternally inherited.
So it could be that part of your ability to live a long, healthy life or your risk or your resilience, right, to those disorders really are conveyed or carried by mitochondria, by your ability to transform energy.
And the reason why through evolution โ
your uniparental inheritance, you get your mitochondria from a single parent, has developed, most people think is because there needs to be a really close metabolic energetic match between the mom and the baby.
The baby comes out and then if the mom has a certain type of metabolism, and we're all different, I hope we talk about how different we are energetically, metabolically.
So we're all very different.
If the baby that was born was like so metabolically different than the mom, there's a chance that there would be a mismatch, right?
And then the mom wouldn't be able to support through breastfeeding historically.