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Dr. Martin Picard

๐Ÿ‘ค Speaker
1629 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Correct.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Okay.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And there were a few papers a few years ago that said, oh, no, look here.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

There's this one case.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

This one kid or these two kids that have paternal father mitochondria.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Turns out it was like a mistake in the sequencing.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So mothers are truly always right.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

I don't know of studies that have asked that question about like subjective energy or like the energy to do stuff and which we can, I think we'll talk more about, but people have looked at other more tractable, which what we do in biomedicine, we take things that we can measure objectively or like, you know, run on the gel or sequence or, you know, objectify with a biomarker in the clinic.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

People have looked at longevity, right?

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Are you more likely to live long if your mom lived long or if your dad lived long?

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Turns out the heritability of longevity is more maternal than paternal.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Are you more likely to have a mental health disorder or to have Parkinson's or Alzheimer's if your mom or your dad had it?

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Some evidence say it's more maternally inherited than paternally inherited.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So it could be that part of your ability to live a long, healthy life or your risk or your resilience, right, to those disorders really are conveyed or carried by mitochondria, by your ability to transform energy.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And the reason why through evolution โ€“

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

your uniparental inheritance, you get your mitochondria from a single parent, has developed, most people think is because there needs to be a really close metabolic energetic match between the mom and the baby.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

The baby comes out and then if the mom has a certain type of metabolism, and we're all different, I hope we talk about how different we are energetically, metabolically.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

So we're all very different.

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

If the baby that was born was like so metabolically different than the mom, there's a chance that there would be a mismatch, right?

Huberman Lab
Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

And then the mom wouldn't be able to support through breastfeeding historically.