Dr. Mary Claire Haver

In my world, yeah, I start with menopause and work my way out from there.

We did that in pregnancy all the time for 24-hour urine collection for protein, you know, for preeclampsia.

So I'm very familiar with that.

To watch for those.

Okay, so on my quick review of what people are stacking on the internet, we talked about H1 and H2 blockers.

What about quercetin?

And we're having a few questions on that.

And what about low histamine diets?

Is there any, is that realistic?

And what about DAO?

Yeah.

When, for anyone listening, would self-experimentation be reasonable and somewhat safe versus you need to go immediately to an allergist?

We can't do it.

I mean, we try to provide resources, books, blogs, podcasts, you know, but I can't give them personal medical information.

The

Where do you think medicine, you know, when we're going for mood symptoms, and that's really big, and we know like across the menopause transition, and we're assigning a lot of it to fluctuating hormones, we see 40% increase in either depression or anxiety.

And that's new diagnosis or someone who was previously well-controlled with their therapy medications, and now they've lost that resilience.

And, you know, what I'm worried about or what this makes me more think about is, you know, how much of that could be what's happening with their immune system being involved in this as well.

So what we're seeing in our group chat is there's a percentage, small, but there is a percentage of patients who seem to develop MCAS or MCAS-like symptoms when they start hormone therapy.

There's something about the formulation, the dose, you know, not all HRT is equal, right?