Dr. Mary Claire Haver

Do we have any ideas on why that happens?

So if a patient comes into your office, Zach, and says, I started Pepsodent and Zyrtec and my PMDD is gone, what do you do with that as a clinician?

You talked about, you believe her.

Right.

Well, for everyone watching, PMDD is premenstrual dysphoric disorder, what you might call PMS or premenstrual syndrome.

So these are women who are debilitated by it's that last week, last two weeks of their cycle, and they're having severe mental health issues.

issues, usually in depression or anxiety.

So I just want to be clear, everyone understood what we were talking about and how for a percentage of patients, these medications are alleviating that.

And there is a mechanistic reason that makes sense, right?

But we don't have any trials.

Yeah.

We had, when we announced it, we had 11,000 likes on the post and

And we had 1,500 questions.

And a huge percentage of the questions centered around, should I do this on my own without talking to a doctor?

Because you can just walk into a pharmacy.

Which ones would I consider?

How safe?

How long?

Can you talk about that a little bit?

So what exactly is MCAS for our followers here, you know, who don't understand what the condition is and how do we make that diagnosis?