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Dr. Matt Walker

๐Ÿ‘ค Speaker
3487 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

And I mentioned that just because at least here in the United States and in many places in the world,

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

that industry is not regulated.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

So it may say 50 milligrams on the bottle.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

You don't really know.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

Now, some of those companies will have what's called third-party laboratory testing where they'll send it out and you can scan a QRI code and you can look at an independent laboratory that tested it and show you the purity of it.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

So that may be one way to go.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

So CBD, I think has some favorable evidence right now.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

If that's the case, let's just assume that you and I speak in another five years time and there's really good data now for this.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

What could be the mechanisms?

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

I think there's at least, there's probably at least two, maybe three mechanisms.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

The first is an indirect mechanism.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

CBD has been demonstrated very nicely in some fantastic studies to be an anxiolytic,

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

which is a fancy term for saying it reduces down your anxiety.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

And earlier, you and I discussed that anxiety and stress is one of the things that will keep you awake.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

So indirectly, it removes this kind of gate that is preventing you from moving down the royal road of sleep.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

And it opens back up the gate because it's removed that gate mechanism, which is high anxiety.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

And by way of being an anxiolytic, it's softened that anxiety and it's easier for you to fall asleep.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

I think that's probably the principal mechanistic bet I would have right now.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

Another indirect mechanism.

Huberman Lab
GUEST SERIES | Dr. Matt Walker: Protocols to Improve Your Sleep

If you look at some of the studies in rats, and we do human work at my sleep center, so we don't do animal studies, but if you look at the data in the rats, CBD can be hypothermic, which means that it drops your core body temperature.