Dr. Matt Walker
๐ค SpeakerAppearances Over Time
Podcast Appearances
And I mentioned that just because at least here in the United States and in many places in the world,
that industry is not regulated.
So it may say 50 milligrams on the bottle.
You don't really know.
Now, some of those companies will have what's called third-party laboratory testing where they'll send it out and you can scan a QRI code and you can look at an independent laboratory that tested it and show you the purity of it.
So that may be one way to go.
So CBD, I think has some favorable evidence right now.
If that's the case, let's just assume that you and I speak in another five years time and there's really good data now for this.
What could be the mechanisms?
I think there's at least, there's probably at least two, maybe three mechanisms.
The first is an indirect mechanism.
CBD has been demonstrated very nicely in some fantastic studies to be an anxiolytic,
which is a fancy term for saying it reduces down your anxiety.
And earlier, you and I discussed that anxiety and stress is one of the things that will keep you awake.
So indirectly, it removes this kind of gate that is preventing you from moving down the royal road of sleep.
And it opens back up the gate because it's removed that gate mechanism, which is high anxiety.
And by way of being an anxiolytic, it's softened that anxiety and it's easier for you to fall asleep.
I think that's probably the principal mechanistic bet I would have right now.
Another indirect mechanism.
If you look at some of the studies in rats, and we do human work at my sleep center, so we don't do animal studies, but if you look at the data in the rats, CBD can be hypothermic, which means that it drops your core body temperature.