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Dr. Matthew Hill

👤 Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I don't know. Yeah. I mean, that being said, a lot of the stuff—now, granted, this was mostly done in the 70s. And, like, this is from my previous life because my undergrad and graduate supervisor, he was a neuroendocrinologist— focused much more on sex hormones and reproductive hormones. So we've written a few reviews. So I've done like reviews on this area. And I know the literature somewhat.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

It's mixed. But generally from the 70s studies, what they would often see is that if they – would serially look at testosterone after someone consumed, they would have little dips. Like that wasn't uncommon for them to find it. Not every study found it. That being said, the kind of range that testosterone stayed in was always the normative range.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

It's mixed. But generally from the 70s studies, what they would often see is that if they – would serially look at testosterone after someone consumed, they would have little dips. Like that wasn't uncommon for them to find it. Not every study found it. That being said, the kind of range that testosterone stayed in was always the normative range.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

It's mixed. But generally from the 70s studies, what they would often see is that if they – would serially look at testosterone after someone consumed, they would have little dips. Like that wasn't uncommon for them to find it. Not every study found it. That being said, the kind of range that testosterone stayed in was always the normative range.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Like it was never that it went so low that someone would have classified as being hypogonadal or would lead to something like gynecomastia, at least from a testosterone deficiency side in terms of the balance between testosterone and estradiol. I don't know as much about the aromatization side of it. Again, I'd say it's pretty mixed.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Like it was never that it went so low that someone would have classified as being hypogonadal or would lead to something like gynecomastia, at least from a testosterone deficiency side in terms of the balance between testosterone and estradiol. I don't know as much about the aromatization side of it. Again, I'd say it's pretty mixed.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Like it was never that it went so low that someone would have classified as being hypogonadal or would lead to something like gynecomastia, at least from a testosterone deficiency side in terms of the balance between testosterone and estradiol. I don't know as much about the aromatization side of it. Again, I'd say it's pretty mixed.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I mean, I don't think the gynecomastia stuff is, I mean, certainly people online might be talking about it and there might be some other components to this. I've also heard, and again, this isn't like science. This is just the same kind of stuff you see on random internet communities. People talking about, oh, well, you know, it has plant estrogens.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I mean, I don't think the gynecomastia stuff is, I mean, certainly people online might be talking about it and there might be some other components to this. I've also heard, and again, this isn't like science. This is just the same kind of stuff you see on random internet communities. People talking about, oh, well, you know, it has plant estrogens.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I mean, I don't think the gynecomastia stuff is, I mean, certainly people online might be talking about it and there might be some other components to this. I've also heard, and again, this isn't like science. This is just the same kind of stuff you see on random internet communities. People talking about, oh, well, you know, it has plant estrogens.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So maybe they're subbing in and having estrogenic effects. I don't know how valid any of this is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So maybe they're subbing in and having estrogenic effects. I don't know how valid any of this is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So maybe they're subbing in and having estrogenic effects. I don't know how valid any of this is.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, absolutely.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, absolutely.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, absolutely.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, and I think that, I mean, when it comes to something like this, I've not seen any compelling evidence for it. So I can't, I certainly wouldn't say that it's a typical side effect that men would experience is like developing breast tissue in response to cannabis. I feel like if that was the case, it would be very known in the scientific community as something that comes out.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, and I think that, I mean, when it comes to something like this, I've not seen any compelling evidence for it. So I can't, I certainly wouldn't say that it's a typical side effect that men would experience is like developing breast tissue in response to cannabis. I feel like if that was the case, it would be very known in the scientific community as something that comes out.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah, and I think that, I mean, when it comes to something like this, I've not seen any compelling evidence for it. So I can't, I certainly wouldn't say that it's a typical side effect that men would experience is like developing breast tissue in response to cannabis. I feel like if that was the case, it would be very known in the scientific community as something that comes out.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Like someone who's on steroids or something.