Dr. Matthew Hill

We'll go with cannabis.

We'll go with cannabis.

We'll go with cannabis.

Okay.

Okay.

Okay.

I mean, I understand it, but yeah, a lot of people don't know.

I mean, I understand it, but yeah, a lot of people don't know.

I mean, I understand it, but yeah, a lot of people don't know.

It's super mixed. So, I mean, you talk about something like prolactin, for example, that is another one that's obviously involved in this whole cascade stuff. Generally, I would say the bulk of the literature actually says that cannabis would suppress prolactin, not increase it. That's the majority of the literature that's out there.

It's super mixed. So, I mean, you talk about something like prolactin, for example, that is another one that's obviously involved in this whole cascade stuff. Generally, I would say the bulk of the literature actually says that cannabis would suppress prolactin, not increase it. That's the majority of the literature that's out there.

It's super mixed. So, I mean, you talk about something like prolactin, for example, that is another one that's obviously involved in this whole cascade stuff. Generally, I would say the bulk of the literature actually says that cannabis would suppress prolactin, not increase it. That's the majority of the literature that's out there.

Probably. I mean, the rodent work would suggest it's through dopamine that's turning off prolactin because you can reverse some of these effects by playing with dopamine signaling. So I don't doubt that's the mechanism. So typically, I would say more often, I mean, there's studies with inhalation and IV that have generally found reduced prolactin.

Probably. I mean, the rodent work would suggest it's through dopamine that's turning off prolactin because you can reverse some of these effects by playing with dopamine signaling. So I don't doubt that's the mechanism. So typically, I would say more often, I mean, there's studies with inhalation and IV that have generally found reduced prolactin.

Probably. I mean, the rodent work would suggest it's through dopamine that's turning off prolactin because you can reverse some of these effects by playing with dopamine signaling. So I don't doubt that's the mechanism. So typically, I would say more often, I mean, there's studies with inhalation and IV that have generally found reduced prolactin.

And in chronic cannabis users, they find somewhat lower resting states of prolactin. That's been found in one study that came out of Yale. Interesting. Testosterone gets a little bit more complicated because... There are a lot of studies that find, A, to begin with, cannabis users may have higher levels of testosterone just at rest.

And in chronic cannabis users, they find somewhat lower resting states of prolactin. That's been found in one study that came out of Yale. Interesting. Testosterone gets a little bit more complicated because... There are a lot of studies that find, A, to begin with, cannabis users may have higher levels of testosterone just at rest.

And in chronic cannabis users, they find somewhat lower resting states of prolactin. That's been found in one study that came out of Yale. Interesting. Testosterone gets a little bit more complicated because... There are a lot of studies that find, A, to begin with, cannabis users may have higher levels of testosterone just at rest.

I don't know. Yeah. I mean, that being said, a lot of the stuff—now, granted, this was mostly done in the 70s. And, like, this is from my previous life because my undergrad and graduate supervisor, he was a neuroendocrinologist— focused much more on sex hormones and reproductive hormones. So we've written a few reviews. So I've done like reviews on this area. And I know the literature somewhat.

I don't know. Yeah. I mean, that being said, a lot of the stuff—now, granted, this was mostly done in the 70s. And, like, this is from my previous life because my undergrad and graduate supervisor, he was a neuroendocrinologist— focused much more on sex hormones and reproductive hormones. So we've written a few reviews. So I've done like reviews on this area. And I know the literature somewhat.