Dr. Matthew Hill
๐ค SpeakerAppearances Over Time
Podcast Appearances
It is, but it's also the timeline because of the fact that with inhalation, it's like a bolus that hits you at once. You get a high blood level. With edibles, it's like the time course. So, I mean, it's going to be like five nanograms per mil, let's say, but it would be like that for a long time. Whereas the 100 nanogram per mil from smoking is like for 20 minutes and then it starts dropping.
It is, but it's also the timeline because of the fact that with inhalation, it's like a bolus that hits you at once. You get a high blood level. With edibles, it's like the time course. So, I mean, it's going to be like five nanograms per mil, let's say, but it would be like that for a long time. Whereas the 100 nanogram per mil from smoking is like for 20 minutes and then it starts dropping.
So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.
So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.
So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.
Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober
Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober
Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober
that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.
that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.
that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.
Potentially, yeah. So, I mean, it is complicated.
Potentially, yeah. So, I mean, it is complicated.
Potentially, yeah. So, I mean, it is complicated.
I would say it's โ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.
I would say it's โ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.
I would say it's โ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.
Yeah.
Yeah.
Yeah.