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Dr. Matthew Hill

๐Ÿ‘ค Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

It is, but it's also the timeline because of the fact that with inhalation, it's like a bolus that hits you at once. You get a high blood level. With edibles, it's like the time course. So, I mean, it's going to be like five nanograms per mil, let's say, but it would be like that for a long time. Whereas the 100 nanogram per mil from smoking is like for 20 minutes and then it starts dropping.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

It is, but it's also the timeline because of the fact that with inhalation, it's like a bolus that hits you at once. You get a high blood level. With edibles, it's like the time course. So, I mean, it's going to be like five nanograms per mil, let's say, but it would be like that for a long time. Whereas the 100 nanogram per mil from smoking is like for 20 minutes and then it starts dropping.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So, but the problem is with the way that you detect it is you can take someone who's a chronic cannabis user and is completely sober and hasn't consumed in a day or two. And their basal levels of THC in their blood may be higher than someone who's profoundly intoxicated by an edible.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Just by the sheer nature of the fact that it would reside in their fat tissue or their brain, it would leak back into the blood. And so you have this issue where, let's say your cutoff was five nanograms per mil, which is for some of the stuff detection thresholds would hover around that area. So you could have someone who's dead sober

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

that tests positive and someone who's profoundly intoxicated who tests negative. So it's like, what's the value in this? It's not telling us anything.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Potentially, yeah. So, I mean, it is complicated.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Potentially, yeah. So, I mean, it is complicated.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Potentially, yeah. So, I mean, it is complicated.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I would say it's โ€“ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I would say it's โ€“ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

I would say it's โ€“ There's nothing that's super clean cut. I mean, I know in the previous podcast, you talked about a prolactin thing.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Yeah.