Menu
Sign In Search Podcasts Libraries Charts People & Topics Add Podcast API Blog Pricing

Dr. Matthew Hill

πŸ‘€ Speaker
1842 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And yeah, so the Charlotte's Web was like, I believe that was what they had named that kind of cannabis that they'd extracted it from. And so it was this, it was a tincture that they were using that was very high CBD content that they were finding was controlling pediatric seizures in kids. Now, this has actually been studied pretty effectively. Most of it's come out of Boston.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Elizabeth Thiel said, has been one of the main leads on this, and she's a neurologist there that has done a lot of the work on this. And so they have, I think, very clearly, and the data is incredibly compelling, their research is one of the reasons why CBD has been descheduled or changed in its scheduling down to a, what is it, a five? What is it, class? CBD? Yeah, like CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Elizabeth Thiel said, has been one of the main leads on this, and she's a neurologist there that has done a lot of the work on this. And so they have, I think, very clearly, and the data is incredibly compelling, their research is one of the reasons why CBD has been descheduled or changed in its scheduling down to a, what is it, a five? What is it, class? CBD? Yeah, like CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Elizabeth Thiel said, has been one of the main leads on this, and she's a neurologist there that has done a lot of the work on this. And so they have, I think, very clearly, and the data is incredibly compelling, their research is one of the reasons why CBD has been descheduled or changed in its scheduling down to a, what is it, a five? What is it, class? CBD? Yeah, like CBD.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So it's been kind of a lot of it's been like shifted in its classification status because it actually has been shown very clearly to have medical benefit. And so it was very specific. It was a very specific form of pediatric epilepsy called Dravet syndrome. Now, there's other forms of pediatric epilepsy I know Elizabeth has studied in addition that has found comparable levels of efficacy.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So it's been kind of a lot of it's been like shifted in its classification status because it actually has been shown very clearly to have medical benefit. And so it was very specific. It was a very specific form of pediatric epilepsy called Dravet syndrome. Now, there's other forms of pediatric epilepsy I know Elizabeth has studied in addition that has found comparable levels of efficacy.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So it's been kind of a lot of it's been like shifted in its classification status because it actually has been shown very clearly to have medical benefit. And so it was very specific. It was a very specific form of pediatric epilepsy called Dravet syndrome. Now, there's other forms of pediatric epilepsy I know Elizabeth has studied in addition that has found comparable levels of efficacy.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But essentially what they have shown is that like very high doses of CBD are are relatively effective at calming down the seizures. In some kids, it's profound. Like in some kids, you're talking about kids that were having dozens of seizures a day to essentially none.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But essentially what they have shown is that like very high doses of CBD are are relatively effective at calming down the seizures. In some kids, it's profound. Like in some kids, you're talking about kids that were having dozens of seizures a day to essentially none.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

But essentially what they have shown is that like very high doses of CBD are are relatively effective at calming down the seizures. In some kids, it's profound. Like in some kids, you're talking about kids that were having dozens of seizures a day to essentially none.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so, and I can understand, I mean, from a grassroots perspective, I can understand if you were a parent who had a child with a disease like this that was largely intractable and not that well controlled from the medications they were on, and then something came around that showed this level of efficacy, you would gravitate towards it. Like, that makes sense to me.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so, and I can understand, I mean, from a grassroots perspective, I can understand if you were a parent who had a child with a disease like this that was largely intractable and not that well controlled from the medications they were on, and then something came around that showed this level of efficacy, you would gravitate towards it. Like, that makes sense to me.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And so, and I can understand, I mean, from a grassroots perspective, I can understand if you were a parent who had a child with a disease like this that was largely intractable and not that well controlled from the medications they were on, and then something came around that showed this level of efficacy, you would gravitate towards it. Like, that makes sense to me.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And I think the work that Elizabeth and her colleagues have done has been really important to establish the efficacy of this, of CBD in these communities. disease states. And so I don't think at this point there's a lot of controversy around that. The question that comes out though is, so how is it working? And we don't have a mechanism.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And I think the work that Elizabeth and her colleagues have done has been really important to establish the efficacy of this, of CBD in these communities. disease states. And so I don't think at this point there's a lot of controversy around that. The question that comes out though is, so how is it working? And we don't have a mechanism.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

And I think the work that Elizabeth and her colleagues have done has been really important to establish the efficacy of this, of CBD in these communities. disease states. And so I don't think at this point there's a lot of controversy around that. The question that comes out though is, so how is it working? And we don't have a mechanism.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So as you had said, like CBD receptor, there is no CBD, like there's no receptor that CBD binds to.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So as you had said, like CBD receptor, there is no CBD, like there's no receptor that CBD binds to.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

So as you had said, like CBD receptor, there is no CBD, like there's no receptor that CBD binds to.

Huberman Lab
Dr. Matthew Hill: How Cannabis Impacts Health & the Potential Risks

Like you can certainly, I mean, you can have products that are made that are like oil-based products, at least, that have a certain amount of CBD and a certain amount of THC. And people do go for those. And there's this – I mean one of the arguments people make is they say, oh, introducing CBD reduces the adverse effects of THC.