Dr. Matthew Hill

At least certainly for PTSD, I would imagine in terms of the context of the nightmares, that's providing some benefit. Whether or not it globally is changing the disease severity or improving the disease, I don't think we really have any evidence to say. But again, I can understand the...

At least certainly for PTSD, I would imagine in terms of the context of the nightmares, that's providing some benefit. Whether or not it globally is changing the disease severity or improving the disease, I don't think we really have any evidence to say. But again, I can understand the...

the desire for people to kind of self-medicate, let's say, by using this as an approach to try and reduce that component of their sleep so that they sleep better, they feel better. Maybe down the road, it would help the prognosis of the disease long-term if it's not sensitized in the same way. But I don't think we have any strong data that we can leverage in that capacity to be able to say it.

the desire for people to kind of self-medicate, let's say, by using this as an approach to try and reduce that component of their sleep so that they sleep better, they feel better. Maybe down the road, it would help the prognosis of the disease long-term if it's not sensitized in the same way. But I don't think we have any strong data that we can leverage in that capacity to be able to say it.

the desire for people to kind of self-medicate, let's say, by using this as an approach to try and reduce that component of their sleep so that they sleep better, they feel better. Maybe down the road, it would help the prognosis of the disease long-term if it's not sensitized in the same way. But I don't think we have any strong data that we can leverage in that capacity to be able to say it.

But to me, it's one of the more interesting areas. I think anxiety disorders in general, there's definitely some potential. So as I had mentioned earlier,

But to me, it's one of the more interesting areas. I think anxiety disorders in general, there's definitely some potential. So as I had mentioned earlier,

But to me, it's one of the more interesting areas. I think anxiety disorders in general, there's definitely some potential. So as I had mentioned earlier,

the the pha inhibitor that elevates anandamide levels so johnson and johnson did do a trial in social anxiety disorder it's published i think from a few years ago at 21 or something i can pull up the reference for that where they did find some benefit it wasn't huge and some of this had to do with the design of the study because they kind of underdosed the patients a bit and so

the the pha inhibitor that elevates anandamide levels so johnson and johnson did do a trial in social anxiety disorder it's published i think from a few years ago at 21 or something i can pull up the reference for that where they did find some benefit it wasn't huge and some of this had to do with the design of the study because they kind of underdosed the patients a bit and so

the the pha inhibitor that elevates anandamide levels so johnson and johnson did do a trial in social anxiety disorder it's published i think from a few years ago at 21 or something i can pull up the reference for that where they did find some benefit it wasn't huge and some of this had to do with the design of the study because they kind of underdosed the patients a bit and so

Not everyone actually showed the elevation in anandamide when they went back and looked, but when they actually isolated the group of people that had higher anandamide, in that proportion of the patients, they did see some symptom improvement. So it did support it. And this is, I mean, very similar.

Not everyone actually showed the elevation in anandamide when they went back and looked, but when they actually isolated the group of people that had higher anandamide, in that proportion of the patients, they did see some symptom improvement. So it did support it. And this is, I mean, very similar.

Not everyone actually showed the elevation in anandamide when they went back and looked, but when they actually isolated the group of people that had higher anandamide, in that proportion of the patients, they did see some symptom improvement. So it did support it. And this is, I mean, very similar.

Like for us, this is a big thing because all of the work that we focused on is looking at how stress and stress hormones regulate anandamide. largely anandamide signaling. And one of the main things that we've demonstrated that's been replicated relatively well over the years is that stress exposure can actually cause a rapid loss of anandamide signaling.

Like for us, this is a big thing because all of the work that we focused on is looking at how stress and stress hormones regulate anandamide. largely anandamide signaling. And one of the main things that we've demonstrated that's been replicated relatively well over the years is that stress exposure can actually cause a rapid loss of anandamide signaling.

Like for us, this is a big thing because all of the work that we focused on is looking at how stress and stress hormones regulate anandamide. largely anandamide signaling. And one of the main things that we've demonstrated that's been replicated relatively well over the years is that stress exposure can actually cause a rapid loss of anandamide signaling.

And it's that loss of anandamide signaling that seems to facilitate some synaptic strengthening in the amygdala and promote activity in areas that are involved in these anxiety circuits. And so... The thought has always been, well, if anandamide, you know, it's that job as its kind of tonic housekeeper at keeping things in that homeostatic range.

And it's that loss of anandamide signaling that seems to facilitate some synaptic strengthening in the amygdala and promote activity in areas that are involved in these anxiety circuits. And so... The thought has always been, well, if anandamide, you know, it's that job as its kind of tonic housekeeper at keeping things in that homeostatic range.

And it's that loss of anandamide signaling that seems to facilitate some synaptic strengthening in the amygdala and promote activity in areas that are involved in these anxiety circuits. And so... The thought has always been, well, if anandamide, you know, it's that job as its kind of tonic housekeeper at keeping things in that homeostatic range.