Dr. Matthew Walker
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Podcast Appearances
That's the relaxation nerve, but it's also a major informational highway, bi-directional communication path between your brain and your gut. That's how we think that the gut can influence the brain. And that's how we think that if you get the gut right, it may be a new approach to a sleep aid because then you can get the brain right.
And it works in the opposite way, which is that when you are sleeping well, it can communicate a signal for improved gut health through the vagus down into the body.
And it works in the opposite way, which is that when you are sleeping well, it can communicate a signal for improved gut health through the vagus down into the body.
And it works in the opposite way, which is that when you are sleeping well, it can communicate a signal for improved gut health through the vagus down into the body.
But when you are not sleeping well, and there's been some great studies, for example, in the extreme with jet lag, my goodness, do you see that when the brain becomes deficient in its sleep through this communication pathway, you will get significant gut dysbiosis. And many people will tell you one of the things that happens when I'm jet lagged is that my tummy is just off.
But when you are not sleeping well, and there's been some great studies, for example, in the extreme with jet lag, my goodness, do you see that when the brain becomes deficient in its sleep through this communication pathway, you will get significant gut dysbiosis. And many people will tell you one of the things that happens when I'm jet lagged is that my tummy is just off.
But when you are not sleeping well, and there's been some great studies, for example, in the extreme with jet lag, my goodness, do you see that when the brain becomes deficient in its sleep through this communication pathway, you will get significant gut dysbiosis. And many people will tell you one of the things that happens when I'm jet lagged is that my tummy is just off.
Oh, my goodness, things don't go well for me. And I don't quite understand why. I'm eating the same things, but it's probably because of this gut dysbiosis caused by a lack of sleep.
Oh, my goodness, things don't go well for me. And I don't quite understand why. I'm eating the same things, but it's probably because of this gut dysbiosis caused by a lack of sleep.
Oh, my goodness, things don't go well for me. And I don't quite understand why. I'm eating the same things, but it's probably because of this gut dysbiosis caused by a lack of sleep.
So it's not been answered yet. I suspect that we have enough data to do the correlation study that you just described, which is, Are these two things related?
So it's not been answered yet. I suspect that we have enough data to do the correlation study that you just described, which is, Are these two things related?
So it's not been answered yet. I suspect that we have enough data to do the correlation study that you just described, which is, Are these two things related?
For example, if you look across a longitudinal study, and if we, I mean, we haven't been assessing the gut microbiome for probably long enough to have good longitudinal data yet in the gut microbiome, but we've got plenty of longitudinal data in sleep, meaning we've started off assessing people in their 30s or their 40s, track them over 15, 20 years,
For example, if you look across a longitudinal study, and if we, I mean, we haven't been assessing the gut microbiome for probably long enough to have good longitudinal data yet in the gut microbiome, but we've got plenty of longitudinal data in sleep, meaning we've started off assessing people in their 30s or their 40s, track them over 15, 20 years,
For example, if you look across a longitudinal study, and if we, I mean, we haven't been assessing the gut microbiome for probably long enough to have good longitudinal data yet in the gut microbiome, but we've got plenty of longitudinal data in sleep, meaning we've started off assessing people in their 30s or their 40s, track them over 15, 20 years,
and then asked, is the sleep that they've been having across their life predictive of their all-cause mortality, cardiovascular mortality, cancer mortality? And we've got that data. What we now need is to look at gut health and ask, as that sleep is declining across the lifespan longitudinally, what happens to the gut?
and then asked, is the sleep that they've been having across their life predictive of their all-cause mortality, cardiovascular mortality, cancer mortality? And we've got that data. What we now need is to look at gut health and ask, as that sleep is declining across the lifespan longitudinally, what happens to the gut?
and then asked, is the sleep that they've been having across their life predictive of their all-cause mortality, cardiovascular mortality, cancer mortality? And we've got that data. What we now need is to look at gut health and ask, as that sleep is declining across the lifespan longitudinally, what happens to the gut?
Yeah, yeah, fantastic.