Dr. Melissa Ilardo

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791 appearances 1 recordings 1 series first heard May 2025 last heard May 2025

Dr. Melissa Ilardo’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · Behaviors That Alter Your Genes to Improve Your Health & Performance | Dr. Melissa Ilardo · 26 May 2025 podcast

Diet is an incredible driver of selection.

So, you know, a very common example of natural selection is lactase persistence.

So our ability to continue to consume milk past infancy.

And that happened very quickly in multiple different human populations.

So it happened in Africa and it happened in Europe.

And another example is the Greenlandic Inuit.

A huge part of their diet was marine mammals that have really high lipid content.

A huge part of their diet was marine mammals that have really high lipid content. And so they actually evolved to be able to better metabolize those lipids so that it wouldn't, you know, kill them from heart disease or something like that. So yeah, diet as a driver of selection is extremely strong. So it may be that this has been shaping our species in ways that we don't even know.

And so they actually evolved to be able to better metabolize those lipids so that it wouldn't, you know, kill them from heart disease or something like that.

So yeah, diet as a driver of selection is extremely strong.

So it may be that this has been shaping our species in ways that we don't even know.

Yeah, so we found two different adaptations.

Yeah, so we found two different adaptations. And I say adaptation, but there's kind of adaptation in a physiological sense, this thing that you can do by training, or adaptation in a genetic sense. And we have found one of each. So the training adaptation that we found was that I mentioned before that when you dive, your heart rate slows down to try to conserve oxygen.

And I say adaptation, but there's kind of adaptation in a physiological sense, this thing that you can do by training, or adaptation in a genetic sense.

And we have found one of each.

So the training adaptation that we found was that I mentioned before that when you dive, your heart rate slows down to try to conserve oxygen.

So their heart rate through a lifetime of training slows down even more. So we could actually – you could visually see this when they were doing these dives – Watching their heart rate, you could just see it plummeting. We had one individual whose heart rate dropped more than 40 beats per minute in less than 15 seconds. Yikes. So really dramatic.

So their heart rate through a lifetime of training slows down even more.

So we could actually – you could visually see this when they were doing these dives –

Watching their heart rate, you could just see it plummeting.

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