Dr. Michael Grandner

The way to stop producing natural melatonin would be aging.

That reduces it.

But to my knowledge, there is no data that shows that continual use of supplementary melatonin changes or reduces your ability to naturally produce it at night.

Is there remodeling?

I don't know.

I haven't seen anything that's concerning in any way.

I just haven't.

There's no finding that when people have looked, it doesn't really seem to be doing that.

It doesn't seem to change the same way other receptors do.

Again, it's a very old system.

It's an old built-in system that is meant to be able to deal with flexibility rather than respond to it super quickly.

I haven't seen anything either.

Maybe findings will come out in the future when people look at it.

This is the other thing that other people need to know.

This is about supplements in general.

That research on supplements is scarce.

especially really well done research in highly controlled conditions, not because, to be honest, not because there's any sort of like conspiracy to keep the information out of people.

It's just that research is extremely expensive to do.

My day job is in research.

That research is extremely expensive to do.