Dr. Michael Kilgard

And so this is really bad if you're an old person to have a hip fracture.

So taking Prozac has off-target effects.

Yeah, yeah.

So serotonin is really important.

The chondrocytes are the cells in the body that make bone.

And when you mess with serotonin, you mess with those.

This is a newly discovered thing for me I didn't know about is that ritalin has effects on growth, right?

So most people now are aware if you take ritalin, you'll end up being about an inch shorter.

This is just an off-target effect.

Many, many positive benefits, but there are some negative, and you have to weigh the pros and cons.

So in this case, we saw all the things we knew the Prozac did, meaning they took the drug.

But their functional ability, their ability to move their hand, wasn't any different.

And why is that?

It's because the range of problems people have is so diverse.

People have all kinds of other insults.

The rats are all perfectly situated in the cage.

They've got exactly the lesion and all the rest.

Why do the first few trials work?

Because they were small, randomized trials with some confirmation bias or some other things implicit to them.

The Food and Drug Administration is serious.