Dr. Michael Snyder

It wasn't just a transient spike.

And so how often you get these – they're called epigenetic modifications.

Happening is not so clear.

But it's now the case you may know with COVID, 2% to 4% of people are becoming diabetic.

after a COVID infection.

So it's not unreasonable to think that they're having epigenetic changes like me.

It hasn't been measured.

That's something we'd like to pursue.

But the effects of these viral infections and stuff, you may know a lot of people get something called chronic fatigue syndrome after some adverse, say, pathogen.

It's not always clear what's causing it.

It seems to be different for different people.

But the idea of these intense stresses, maybe from a viral infection or other pathogen,

triggering some long-term chronic effects is maybe more common than people realize for autoimmune disease, for chronic fatigue syndrome, in my case for diabetes, maybe, as I say, more prevalent than people realize.

Once again, that homeostatic system concept that you're – yeah, maybe if your genetics is a little bit weaker, we've noticed that we found a new –

if you will, set of genes involved in ALS and that those genes tend to be underexpressed and, you know, called IPS-derived motor neurons, the relevant cell types for ALS patients.

So it may be that, you know, if your genetics is a little weaker in some areas than others and other things could trigger that sort of thing.

So I like that general concept that we're – in some cases, maybe that's beneficial.

I'm not saying getting ALS is beneficial, but maybe we're attuned certain ways because in ancient times, we had to deal with things like TB and stuff and the idea that you would be – well, the classic is sickle cell, right?

Folks with sickle cell mutations might be more resistant to malaria.

So maybe some of this tuning helps you in some ways but is adverse in other ways or –