Dr. Mink Chawla

Or hepatitis B is probably the best example. There's one face. And if I can get the body to make antibodies to that epitope, I can actually make this person immune to this. So what you have to do now is you have to make metric tons of these little faces. That is really expensive. And that takes a lot of time. Now, I'll tell you a funny story. When I entered from academics to industry,

due to my chronic foot and mouth disease. I was at this big meeting, and we were talking about how this one company was having difficulty making some product. Now, at the time, I didn't know that 80% of FDA denials come from not being able to make your product correctly, because it's really hard. I didn't know that at the time.

due to my chronic foot and mouth disease. I was at this big meeting, and we were talking about how this one company was having difficulty making some product. Now, at the time, I didn't know that 80% of FDA denials come from not being able to make your product correctly, because it's really hard. I didn't know that at the time.

due to my chronic foot and mouth disease. I was at this big meeting, and we were talking about how this one company was having difficulty making some product. Now, at the time, I didn't know that 80% of FDA denials come from not being able to make your product correctly, because it's really hard. I didn't know that at the time.

Had I known that, I wouldn't have said what I said, which I'm going to tell you what I said. So they're complaining, they can't make this thing. And it was a really great drug. And I'm like, how hard could it be? It's yellow and blue, Play-Doh makes green. But that was the wrong thing to say. He didn't make any friends. Making stuff is really hard.

Had I known that, I wouldn't have said what I said, which I'm going to tell you what I said. So they're complaining, they can't make this thing. And it was a really great drug. And I'm like, how hard could it be? It's yellow and blue, Play-Doh makes green. But that was the wrong thing to say. He didn't make any friends. Making stuff is really hard.

Had I known that, I wouldn't have said what I said, which I'm going to tell you what I said. So they're complaining, they can't make this thing. And it was a really great drug. And I'm like, how hard could it be? It's yellow and blue, Play-Doh makes green. But that was the wrong thing to say. He didn't make any friends. Making stuff is really hard.

Now, when you say that at a large public meeting and your chief medical officer of a company that comes back to bite you on the ass forever. Oh yeah. And I deserved it. And so I get like Play-Doh, like joke things from these guys. I mean, it's fine. Like I deserve it. Oh my God. They send me like, you know, it's so easy. Even a CMO can do it.

Now, when you say that at a large public meeting and your chief medical officer of a company that comes back to bite you on the ass forever. Oh yeah. And I deserved it. And so I get like Play-Doh, like joke things from these guys. I mean, it's fine. Like I deserve it. Oh my God. They send me like, you know, it's so easy. Even a CMO can do it.

Now, when you say that at a large public meeting and your chief medical officer of a company that comes back to bite you on the ass forever. Oh yeah. And I deserved it. And so I get like Play-Doh, like joke things from these guys. I mean, it's fine. Like I deserve it. Oh my God. They send me like, you know, it's so easy. Even a CMO can do it.

Like it's like these very funny, you know, joke memes, you know, on Play-Doh. But making stuff is really hard. So this is where the mRNA vaccine comes into play. So the idea is that, It's expensive to set up a factory. It's expensive to take all this virus and make all of it. Instead of having a factory make it, let's have the body make it. That's how the mRNA vaccine works.

Like it's like these very funny, you know, joke memes, you know, on Play-Doh. But making stuff is really hard. So this is where the mRNA vaccine comes into play. So the idea is that, It's expensive to set up a factory. It's expensive to take all this virus and make all of it. Instead of having a factory make it, let's have the body make it. That's how the mRNA vaccine works.

Like it's like these very funny, you know, joke memes, you know, on Play-Doh. But making stuff is really hard. So this is where the mRNA vaccine comes into play. So the idea is that, It's expensive to set up a factory. It's expensive to take all this virus and make all of it. Instead of having a factory make it, let's have the body make it. That's how the mRNA vaccine works.

So the trick and why the technology is really slick is we, all our cells, make proteins. And there are little factories inside our cells called ribosomes. And they are protein makers. That's what they do for a making. We need protein. We make muscle. We make antibodies. And these little guys, this is what they do for a living.

So the trick and why the technology is really slick is we, all our cells, make proteins. And there are little factories inside our cells called ribosomes. And they are protein makers. That's what they do for a making. We need protein. We make muscle. We make antibodies. And these little guys, this is what they do for a living.

So the trick and why the technology is really slick is we, all our cells, make proteins. And there are little factories inside our cells called ribosomes. And they are protein makers. That's what they do for a making. We need protein. We make muscle. We make antibodies. And these little guys, this is what they do for a living.

So they get a set of instructions from the nucleus, the brain of the cell, and that is message mRNA. So the message goes from the nucleus to the ribosome. So the blueprint goes from the brain to the factory, the ribosome, make this protein. So the idea is let's hijack that ribosome and have it make this face so that the body will respond to it. So we bypass the factory. The body is the factory.

So they get a set of instructions from the nucleus, the brain of the cell, and that is message mRNA. So the message goes from the nucleus to the ribosome. So the blueprint goes from the brain to the factory, the ribosome, make this protein. So the idea is let's hijack that ribosome and have it make this face so that the body will respond to it. So we bypass the factory. The body is the factory.

So they get a set of instructions from the nucleus, the brain of the cell, and that is message mRNA. So the message goes from the nucleus to the ribosome. So the blueprint goes from the brain to the factory, the ribosome, make this protein. So the idea is let's hijack that ribosome and have it make this face so that the body will respond to it. So we bypass the factory. The body is the factory.

Brilliant. Okay, here's two problems that happen. So the first problem is viruses, and we're trying to do this to us for a long time too. Even before we came up with this idea, viruses were doing it.