Dr. Nathan Bryan

Well, I think it's, you know, it's certainly moderate alcohol consumption has some cytoprotective, cardioprotective properties. And so what happens is when you have moderate alcohol consumption, and we're talking maybe one or two drinks every couple of days, right? What that does is it's called alcohol or ethanol preconditioning. And this has been studied for 30 or 40 years.

And the observation was that people who drink moderate alcohol, if they have a heart attack, the heart is a little bit protected from injury from someone who hasn't consumed alcohol. It's ethanol preconditioning. So it's upregulating an enzyme called aldehyde dehydrogenase, which is an enzyme that's responsible for metabolizing and prolonging nitric oxide activity. So there's a clear connection.

And the observation was that people who drink moderate alcohol, if they have a heart attack, the heart is a little bit protected from injury from someone who hasn't consumed alcohol. It's ethanol preconditioning. So it's upregulating an enzyme called aldehyde dehydrogenase, which is an enzyme that's responsible for metabolizing and prolonging nitric oxide activity. So there's a clear connection.

And the observation was that people who drink moderate alcohol, if they have a heart attack, the heart is a little bit protected from injury from someone who hasn't consumed alcohol. It's ethanol preconditioning. So it's upregulating an enzyme called aldehyde dehydrogenase, which is an enzyme that's responsible for metabolizing and prolonging nitric oxide activity. So there's a clear connection.

However, the problem with overdoing alcohol consumption, you get portal hypertension, you get liver disease, and it destroys nitric oxide production, leads to inflammation, oxidative stress, and immune dysfunction. I think what we're finding is, and the other thing people ask me all the time too, what about drinking alcohol and affecting the oral microbiome? Because we know alcohol-based mouthwash

However, the problem with overdoing alcohol consumption, you get portal hypertension, you get liver disease, and it destroys nitric oxide production, leads to inflammation, oxidative stress, and immune dysfunction. I think what we're finding is, and the other thing people ask me all the time too, what about drinking alcohol and affecting the oral microbiome? Because we know alcohol-based mouthwash

However, the problem with overdoing alcohol consumption, you get portal hypertension, you get liver disease, and it destroys nitric oxide production, leads to inflammation, oxidative stress, and immune dysfunction. I think what we're finding is, and the other thing people ask me all the time too, what about drinking alcohol and affecting the oral microbiome? Because we know alcohol-based mouthwash

Kill it. But I tell people, at least when I drink a scotch, I'm not holding in my mouth for 30 or 60 seconds and swishing it around. So the alcohol in spirits in wine doesn't have a resident time long enough in the oral cavity to disrupt the microbiome.

Kill it. But I tell people, at least when I drink a scotch, I'm not holding in my mouth for 30 or 60 seconds and swishing it around. So the alcohol in spirits in wine doesn't have a resident time long enough in the oral cavity to disrupt the microbiome.

Kill it. But I tell people, at least when I drink a scotch, I'm not holding in my mouth for 30 or 60 seconds and swishing it around. So the alcohol in spirits in wine doesn't have a resident time long enough in the oral cavity to disrupt the microbiome.

You know, if we're talking about moderate consumption and not over consumption, again, and this is not my opinion, it's based on published science. But I think it's somewhere in the middle. It's probably a D. I'll give it a D. Can you give it a D?

You know, if we're talking about moderate consumption and not over consumption, again, and this is not my opinion, it's based on published science. But I think it's somewhere in the middle. It's probably a D. I'll give it a D. Can you give it a D?

You know, if we're talking about moderate consumption and not over consumption, again, and this is not my opinion, it's based on published science. But I think it's somewhere in the middle. It's probably a D. I'll give it a D. Can you give it a D?

It's not extremely beneficial. I mean, there are other ways that lead to cytoprotection, cardioprotection that are probably more health-promoting than alcohol consumption. But it's certainly not an F.

It's not extremely beneficial. I mean, there are other ways that lead to cytoprotection, cardioprotection that are probably more health-promoting than alcohol consumption. But it's certainly not an F.

It's not extremely beneficial. I mean, there are other ways that lead to cytoprotection, cardioprotection that are probably more health-promoting than alcohol consumption. But it's certainly not an F.

Well, we've known, we've learned over the past 40 years in this entire science of nitric oxide over 200,000 scientific papers published in the scientific and medical literature. So nitric oxide controls important things like blood pressure, sexual function, cognitive function. It controls inflammation, oxidative stress, and immune dysfunction, the hallmarks of chronic disease.

Well, we've known, we've learned over the past 40 years in this entire science of nitric oxide over 200,000 scientific papers published in the scientific and medical literature. So nitric oxide controls important things like blood pressure, sexual function, cognitive function. It controls inflammation, oxidative stress, and immune dysfunction, the hallmarks of chronic disease.

Well, we've known, we've learned over the past 40 years in this entire science of nitric oxide over 200,000 scientific papers published in the scientific and medical literature. So nitric oxide controls important things like blood pressure, sexual function, cognitive function. It controls inflammation, oxidative stress, and immune dysfunction, the hallmarks of chronic disease.

It's involved in insulin signaling and glucose uptake. So we know today that the functional loss of nitric oxide inside the human body is the earliest event in the onset progression of most, I think probably all, age-related chronic disease. So if you're doing things that are disrupting nitric oxide production, that sets the stage for rapid acceleration, onset and progression of chronic disease.