Dr. Nathan Bryan

It's involved in insulin signaling and glucose uptake. So we know today that the functional loss of nitric oxide inside the human body is the earliest event in the onset progression of most, I think probably all, age-related chronic disease. So if you're doing things that are disrupting nitric oxide production, that sets the stage for rapid acceleration, onset and progression of chronic disease.

It's involved in insulin signaling and glucose uptake. So we know today that the functional loss of nitric oxide inside the human body is the earliest event in the onset progression of most, I think probably all, age-related chronic disease. So if you're doing things that are disrupting nitric oxide production, that sets the stage for rapid acceleration, onset and progression of chronic disease.

If we can maintain optimal nitric oxide production, both the basic science and the clinical science tells us that we can prevent or delay onset of age-related disease, cardiovascular disease, diabetes, vascular dementia, Alzheimer's. Everything we know about chronic disease revolves around poor blood flow, inflammation, oxidative stress, and immune dysfunction. And nitric oxide corrects all four.

If we can maintain optimal nitric oxide production, both the basic science and the clinical science tells us that we can prevent or delay onset of age-related disease, cardiovascular disease, diabetes, vascular dementia, Alzheimer's. Everything we know about chronic disease revolves around poor blood flow, inflammation, oxidative stress, and immune dysfunction. And nitric oxide corrects all four.

If we can maintain optimal nitric oxide production, both the basic science and the clinical science tells us that we can prevent or delay onset of age-related disease, cardiovascular disease, diabetes, vascular dementia, Alzheimer's. Everything we know about chronic disease revolves around poor blood flow, inflammation, oxidative stress, and immune dysfunction. And nitric oxide corrects all four.

You know, smoking with all the data, all the warning signs, even on the cigarette packages themselves, yet people still smoke. And I get it. It's an addiction. They know it's bad for them, but they get pleasure out of it. But smoking is absolute at the bottom. It's probably the worst thing you could do.

You know, smoking with all the data, all the warning signs, even on the cigarette packages themselves, yet people still smoke. And I get it. It's an addiction. They know it's bad for them, but they get pleasure out of it. But smoking is absolute at the bottom. It's probably the worst thing you could do.

You know, smoking with all the data, all the warning signs, even on the cigarette packages themselves, yet people still smoke. And I get it. It's an addiction. They know it's bad for them, but they get pleasure out of it. But smoking is absolute at the bottom. It's probably the worst thing you could do.

Interestingly, though, cigarette smoke, people who are smoking, we can detect nitric oxide gas coming off the burning cigarette. And we actually did, when I was in Boston, I believe we had a grant looking at the effects of nitric oxide and cigarette smoke on cardiovascular health.

Interestingly, though, cigarette smoke, people who are smoking, we can detect nitric oxide gas coming off the burning cigarette. And we actually did, when I was in Boston, I believe we had a grant looking at the effects of nitric oxide and cigarette smoke on cardiovascular health.

Interestingly, though, cigarette smoke, people who are smoking, we can detect nitric oxide gas coming off the burning cigarette. And we actually did, when I was in Boston, I believe we had a grant looking at the effects of nitric oxide and cigarette smoke on cardiovascular health.

So I think what we figured out was there's so many toxic things in cigarette smoke that it certainly outweighs the small benefit you may get from the little bit of nitric oxide that's found in cigarette smoke.

So I think what we figured out was there's so many toxic things in cigarette smoke that it certainly outweighs the small benefit you may get from the little bit of nitric oxide that's found in cigarette smoke.

So I think what we figured out was there's so many toxic things in cigarette smoke that it certainly outweighs the small benefit you may get from the little bit of nitric oxide that's found in cigarette smoke.

No, they're nicotinic receptors inside the body. So nicotine is a vasoconstrictor. So when we have nicotine, it constricts the blood vessels. But there are many other kind of extravascular effects of activating the nicotinic receptors and the effects of nicotine. But it makes people feel good. I mean, it's an addictive substance. That's why people smoke.

No, they're nicotinic receptors inside the body. So nicotine is a vasoconstrictor. So when we have nicotine, it constricts the blood vessels. But there are many other kind of extravascular effects of activating the nicotinic receptors and the effects of nicotine. But it makes people feel good. I mean, it's an addictive substance. That's why people smoke.

No, they're nicotinic receptors inside the body. So nicotine is a vasoconstrictor. So when we have nicotine, it constricts the blood vessels. But there are many other kind of extravascular effects of activating the nicotinic receptors and the effects of nicotine. But it makes people feel good. I mean, it's an addictive substance. That's why people smoke.

That's why people dip snuff or chew tobacco. And now you've got the nicotine in the vapes that are rampant. But again... Nicotine is one of these naturally occurring substances, and we have nicotinic receptors just like we have endocannabinoid receptors. So our body is used to seeing these things and initiating some signaling aspect.

That's why people dip snuff or chew tobacco. And now you've got the nicotine in the vapes that are rampant. But again... Nicotine is one of these naturally occurring substances, and we have nicotinic receptors just like we have endocannabinoid receptors. So our body is used to seeing these things and initiating some signaling aspect.

That's why people dip snuff or chew tobacco. And now you've got the nicotine in the vapes that are rampant. But again... Nicotine is one of these naturally occurring substances, and we have nicotinic receptors just like we have endocannabinoid receptors. So our body is used to seeing these things and initiating some signaling aspect.