Dr. Nathan Bryan

So when you have an elevation, chronic elevation of cortisol, I mean, that's a normal stress response. We need that acutely. But when you're chronically stressed, then it completely shuts down and disturbs other hormones and the whole endocrine system.

And it'll eventually shut down nitric oxide production because you're inflamed, you develop oxidative stress, and you develop an immune dysfunction.

And it'll eventually shut down nitric oxide production because you're inflamed, you develop oxidative stress, and you develop an immune dysfunction.

And it'll eventually shut down nitric oxide production because you're inflamed, you develop oxidative stress, and you develop an immune dysfunction.

Yeah, we call that hormesis in terms of how the body adapts to, because when we exercise or when we go for a run or when we do a cold plunge, it's an acute stress on the body. So the body then transduces an adaptive response. So like resistance training, there's intermittent hypoxia when we contract our muscles. It's squeezing on the blood supply. and then it's causing intermittent hypoxia.

Yeah, we call that hormesis in terms of how the body adapts to, because when we exercise or when we go for a run or when we do a cold plunge, it's an acute stress on the body. So the body then transduces an adaptive response. So like resistance training, there's intermittent hypoxia when we contract our muscles. It's squeezing on the blood supply. and then it's causing intermittent hypoxia.

Yeah, we call that hormesis in terms of how the body adapts to, because when we exercise or when we go for a run or when we do a cold plunge, it's an acute stress on the body. So the body then transduces an adaptive response. So like resistance training, there's intermittent hypoxia when we contract our muscles. It's squeezing on the blood supply. and then it's causing intermittent hypoxia.

So the body responds with angiogenesis. We're creating more blood vessels. So now with that same resistance, we're not developing hypoxia because now we revascularize that tissue. We develop, you know, we build more protein, we build more muscle, and that's, you know, the benefits of weight training.

So the body responds with angiogenesis. We're creating more blood vessels. So now with that same resistance, we're not developing hypoxia because now we revascularize that tissue. We develop, you know, we build more protein, we build more muscle, and that's, you know, the benefits of weight training.

So the body responds with angiogenesis. We're creating more blood vessels. So now with that same resistance, we're not developing hypoxia because now we revascularize that tissue. We develop, you know, we build more protein, we build more muscle, and that's, you know, the benefits of weight training.

For instance, when we run, you know, if you're doing a marathon and you're running for two to three hours, you're completely diverting blood flow away from the kidneys, the intestines, and some people can develop ischemic organ disease. But the body adapts to that and go, oh, I don't want to run out of oxygen again. I need more mitochondria. Turns on mitochondrial biogenesis.

For instance, when we run, you know, if you're doing a marathon and you're running for two to three hours, you're completely diverting blood flow away from the kidneys, the intestines, and some people can develop ischemic organ disease. But the body adapts to that and go, oh, I don't want to run out of oxygen again. I need more mitochondria. Turns on mitochondrial biogenesis.

For instance, when we run, you know, if you're doing a marathon and you're running for two to three hours, you're completely diverting blood flow away from the kidneys, the intestines, and some people can develop ischemic organ disease. But the body adapts to that and go, oh, I don't want to run out of oxygen again. I need more mitochondria. Turns on mitochondrial biogenesis.

It improves the oxygen utilization. So now that cell can make more energy with less oxygen. And why is that? Because it was confronted, it dealt with a stress, an acute stress. And that's kind of like the cold plunge. When I go from the sauna, 170 degrees to 37 degrees, it's flexing the blood vessels. Because when you're hot in a sauna, your blood vessels are maximally dilated.

It improves the oxygen utilization. So now that cell can make more energy with less oxygen. And why is that? Because it was confronted, it dealt with a stress, an acute stress. And that's kind of like the cold plunge. When I go from the sauna, 170 degrees to 37 degrees, it's flexing the blood vessels. Because when you're hot in a sauna, your blood vessels are maximally dilated.

It improves the oxygen utilization. So now that cell can make more energy with less oxygen. And why is that? Because it was confronted, it dealt with a stress, an acute stress. And that's kind of like the cold plunge. When I go from the sauna, 170 degrees to 37 degrees, it's flexing the blood vessels. Because when you're hot in a sauna, your blood vessels are maximally dilated.

trying to rid the body of the heat so it doesn't overheat. Then when you go to cold, the body's trying to preserve heat so it constricts all the blood vessels. But for me, it's like weight training for your blood vessels because there's smooth muscle that's around all the blood vessels and it's working them out. But it's stressful. But the adaptive effects to that acute stress

trying to rid the body of the heat so it doesn't overheat. Then when you go to cold, the body's trying to preserve heat so it constricts all the blood vessels. But for me, it's like weight training for your blood vessels because there's smooth muscle that's around all the blood vessels and it's working them out. But it's stressful. But the adaptive effects to that acute stress

trying to rid the body of the heat so it doesn't overheat. Then when you go to cold, the body's trying to preserve heat so it constricts all the blood vessels. But for me, it's like weight training for your blood vessels because there's smooth muscle that's around all the blood vessels and it's working them out. But it's stressful. But the adaptive effects to that acute stress

Well, we have to move. I mean, humans are designed to be mobile, to move. And yet most Americans aren't. We get in our car, we drive to work, we sit for six, eight, ten hours a day. Nobody gets exercise. And then the calories we consume through diet are stored as fat and become unhealthy.