Dr. Nathan Bryan

Well, because you're killing the oral microbiome that's partly responsible for production of nitric oxide.

And nitric oxide.

Without nitric oxide, you get constriction of blood vessels, and it leads to high blood pressure.

Yeah, so this is a two-way street.

So in men, testosterone activates nitric oxide production.

Okay.

In women, estrogen activates and stimulates nitric oxide production.

Okay.

So as long as we have optimal sex hormones, and as long as the enzyme in the lining of the blood vessel can functionally produce nitric oxide, that explains the cardioprotective benefits of hormone replacement therapy.

As long as the enzyme is functional and coupled.

which means that we have to understand the enzymology and biochemistry of that reaction to where when it's exposed to testosterone, the cell can actually make nitric oxide in response.

Well, think about it.

I mean, there's other agonists too, like vitamin D. I mean, most Americans are deficient in vitamin D. People with low testosterone have erectile dysfunction.

And why is that?

Because they're not stimulating nitric oxide production and they're not dilating the blood vessels, so they develop ED.

So all of this, no matter what it is, whether it's related to vitamin D deficiency, which is activating or stimulating nitric oxide, if it's low hormones, if it's a poor diet, sedentary lifestyle, all of that can be explained by insufficient nitric oxide production.

I think the same answer is for that too.

It's not so much what we should be eating, it's what we should not be eating.

Okay.

So we'll cover those step by step.