Dr. Nolan Williams

And this generation of psychedelic researchers are really clear about that.

I think the 60s folks were not clear about that and they felt like there was this whole kind of cultural thing that was going on there.

But I think this cohort of individuals really understands that in order to really make this happen, we have to understand that if you need a prescription,

for an SSRI, which doesn't change your consciousness a whole lot, and we're very worried about that, and the doctor has to evaluate you for that every week, that the idea that some of these substances would go outside of very strict medical supervision is kind of preposterous, actually.

It's kind of a dumb moment, I think, for all of medicine to say, look, we've

If we're going to do this right, we've got to do it in such a way that's so protected, that's so safe, that we make sure people know these things are not recreational and they're really for the pure purposes of really powerfully changing cognition for a while and letting people have these.

what seem to be relatively therapeutic states.

Yeah, yeah, definitely.

Ayahuasca is another psychedelic.

It's used as a sacrament in Brazil and in Peru and Ecuador and Colombia, so a lot of the South American countries.

And what they do is they combine two plants together where one plant of the two plant combination would effectively do nothing.

but the two plant combination together is capable of producing this very profound psychedelic effect.

And what's really kind of

Curious is that there are, as I understand it, 10 to 20,000 plant species in the Amazon.

And somehow somebody combined these two plants together in certain proportionality and cooked this for five, 10 hours to the point where you cook out the dimethyltryptamine out of one of the plants and cook out the reversible monoamine oxidase inhibitor out of the other plant.

it's such a way that the reversible monoamine oxidase inhibitor prevents the the gi breakdown of the dimethyltryptamine in such a way that it's then allowed to cross the blood brain barrier and get into the brain and if you didn't add the reversible monoamine oxidase inhibitor plant derived into this combination then it would never cross the brain

if you put people on a standard psychiatry prescribed monoimmune oxidase inhibitor that wasn't reversible, you'd throw them into serotonin syndrome, right?

So this kind of like sweet spot that somehow ayahuasca practitioners have found of being able to get DMT into the brain from an oral source with this combination of a monoimmune oxidase inhibitor is curious.

And so that substance has been explored as an antidepressant agent, and some studies have looked at that.

It also seems to be very safe.