Dr. Nolan Williams

to kind of have a convergent theory on this.

It's still to be determined.

There's still a lot of work, I think, that needs to be done.

But it's certainly suggestive that there's pretty profound changes in brain activity and brain connectivity after.

And what we've found to be really interesting

is the antidepressant effects of psilocybin have a particular connectivity change that we also see with our TMS approaches, right?

And it's this connectivity between the subgenual anterior cingulate and the default mode network.

And so when we do this effective Stanford neuromodulation therapy stimulation, we see a down regulation, the connectivity between the negatively valenced mood state in the case of depressed individuals and the self-representation of the brain.

And you see that same connectivity change occur post-psilocybin, you know, suggesting there's a convergent mechanism.

And it makes sense, right?

You've kind of got an over-connected, negatively valenced system, conflict system that's kind of

kind of attached on to the self-representation and people feel stuck, right?

And then when you do whatever you do that's effective, it unpairs those two systems.

Ibogaine is one of the

alkaloids that you can extract from an iboga tree root bark that's typically growing in the country of Gabon, Africa.

So what individuals taking Ibogaine will say is that open eyes, they don't see anything, but closed eyes, they'll go back through and re-experience earlier life

memories and they will be able to experience it from a place of empathy not only for themselves but from others and kind of a detached empathy and being able to see this as almost a third party even though they were there

Ibogaine is in no way a recreational substance.

You're essentially having this what they call a life review.

They also call it 10 years of psychotherapy in a night.