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Dr. Nolan Williams

๐Ÿ‘ค Speaker
272 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

So these are the terminology that people talk about.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Is it truly one night?

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Depending upon how fast you metabolize it, sometimes 24, sometimes 36 hours.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Sometimes it can be shorter, but it is a long time.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

It's a very long time.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

So it's definitely the longest acting psychedelic substance I know of.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

And so we have over the last couple of years been able to do this first in human kind of full neurobiological clinical neurocognitive evaluation of what

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

ibogaine is doing in this case in in special operations special forces individuals former navy seals for me army rangers that that kind of crew of folks and look at the pre-post changes that we that they're experienced to be able to totally quantitate all of that and so we've been able to capture all the clinical scales you know depression scales ptsd scales all that standard stuff neurocognitive batteries so how does your executive function work specifically how does your verbal memory all of that

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

and then neuroimaging and EEG.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

So this will be the first human study of ibogaine for those.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

And the reason why is because ibogaine's kind of the, both seemingly the most potent and most effective

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

seemingly to me at least most powerful psychedelic but the one that has the most risk too because it has a cardiac effect it seems to be that you can screen people out that have risk off of their electrocardiogram and reduce the risk quite a bit and that's what we all did but that's why people haven't really studied it as much and it isn't as in addition nobody goes to a rave on Ibogaine there's no recreation at all with it it's not fun

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

People say that it's relieving, but it's hard work, right?

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Because, yeah, you're reexamining things.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

So then we see these folks after, and I'll tell you, you know, we haven't fully analyzed the data yet, but I'll tell you that from what my folks are telling me, it's pretty dramatic.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

You know, people come back and they're doing a lot better.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Soldiers experience something called moral injury, right, where they...

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

Maybe they accidentally blew something up and it had a kid in it or something like that.

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

If they're in Afghanistan or Iraq, maybe a child died on accident or maybe a civilian died or whatever it was, right?

Huberman Lab
Essentials: Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams

And they suffer these moral injuries as part of the job.