Dr. Patrick Soon-Shiong
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The second thing it wipes out is cells called neutrophils that prevent infection. And there's a drug for that called neupogen. But the most important thing that wipes out is your NK and T cells, and that's called lymphocytes. So Drew, I'd like you to test this with your oncology friends and say, when you do a CBC, which is a standard blood test, what do you look for to treat your patient?
Well, we look for anemia and we look for neutropenia. And well, do you look for your lymphocyte count? No. Why? We don't bother about it because there's no treatment for that. It turns out the only thing that protects your body against cancer is your lymphocytes, meaning the NK cells and T cells. And there was no treatment for that for 35 years until last year, 2024, when I got approved, ANGTEVA.
Well, we look for anemia and we look for neutropenia. And well, do you look for your lymphocyte count? No. Why? We don't bother about it because there's no treatment for that. It turns out the only thing that protects your body against cancer is your lymphocytes, meaning the NK cells and T cells. And there was no treatment for that for 35 years until last year, 2024, when I got approved, ANGTEVA.
That's now being used in Lynch syndrome and where we have bladder cancer patients now free of disease and complete response over nine years. Patients were about to lose their bladder BCG unresponsive, free of disease over 54 months because we've driven memory T cells. The reason I'm able to say this to you is because it's in the package insert. It is actually in the label.
That's now being used in Lynch syndrome and where we have bladder cancer patients now free of disease and complete response over nine years. Patients were about to lose their bladder BCG unresponsive, free of disease over 54 months because we've driven memory T cells. The reason I'm able to say this to you is because it's in the package insert. It is actually in the label.
It is the first drug to activate your NK cells, your T cells, and your memory T cells. So that's why I'm saying what is simple and profound. Meaning that we now know that anybody getting chemotherapy, anybody getting radiation, within a day or two, you wipe out the only cells that matter, i.e. the cells that kill cancer. And for 35 years, we've never had a treatment for that.
It is the first drug to activate your NK cells, your T cells, and your memory T cells. So that's why I'm saying what is simple and profound. Meaning that we now know that anybody getting chemotherapy, anybody getting radiation, within a day or two, you wipe out the only cells that matter, i.e. the cells that kill cancer. And for 35 years, we've never had a treatment for that.
That is where I'm going down the line when we talk about long COVID. Because when you have viral infection, the first thing you wipe out, the virus is smart. It wipes out the T cells and NK cells.
That is where I'm going down the line when we talk about long COVID. Because when you have viral infection, the first thing you wipe out, the virus is smart. It wipes out the T cells and NK cells.
So, but you can see the complexity of what I just said to you is a science lesson.
So, but you can see the complexity of what I just said to you is a science lesson.
And Epigen would cause blood clotting. But you know, the irony is that they need Epigen and Neupogen because of what we've done to the patient. We've given them chemotherapy. And the same thing we've done to that patient is actually wiped out the cells that matter, the NK and T cells.
And Epigen would cause blood clotting. But you know, the irony is that they need Epigen and Neupogen because of what we've done to the patient. We've given them chemotherapy. And the same thing we've done to that patient is actually wiped out the cells that matter, the NK and T cells.
So my fight for the last 20 years is here's a surgeon from South Africa, this doctor working on pancreas transplant and talking to oncologists and says, everything we've been doing so far has been wrong. We've actually treated cancer wrongly.
So my fight for the last 20 years is here's a surgeon from South Africa, this doctor working on pancreas transplant and talking to oncologists and says, everything we've been doing so far has been wrong. We've actually treated cancer wrongly.
We should use, when I tried to develop a Braxane, I wanted to use the lowest dose possible because a Braxane was to actually convert these macrophages called M2 to M1s, which are killer macrophages. So when you ask, am I an immunologist? Am I a surgeon? Am I an oncologist? Am I a virologist? By the way, if you're a virologist, you'll only think about these antibodies. You never think of T-cells.
We should use, when I tried to develop a Braxane, I wanted to use the lowest dose possible because a Braxane was to actually convert these macrophages called M2 to M1s, which are killer macrophages. So when you ask, am I an immunologist? Am I a surgeon? Am I an oncologist? Am I a virologist? By the way, if you're a virologist, you'll only think about these antibodies. You never think of T-cells.
So this problem with medicine, we've siloed ourselves into these little blocks. Oh, my God. Yes. And therefore, our thinking is so myopic. And if you have a broad scale scope of comprehensive thinking of the biology of the human being, you thought it was a quack. And here we have people like RFK who are really asking the right questions. And I agree with those questions.
So this problem with medicine, we've siloed ourselves into these little blocks. Oh, my God. Yes. And therefore, our thinking is so myopic. And if you have a broad scale scope of comprehensive thinking of the biology of the human being, you thought it was a quack. And here we have people like RFK who are really asking the right questions. And I agree with those questions.
And I sure hope it's confirmed. I'm not sure when the vote is, but I sure hope it'll be confirmed. Yeah.