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Dr. Peter Attia

👤 Speaker
11186 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And frankly, a lot of people just, I mean, I used to even get nauseous on Flexeril. But something about Baclofen, I don't even know it's in me at 20 milligrams twice a day, but it actually takes the edge off. And where I typically find this beneficial is is if I slept wrong and I get a kink in my trap, or I've been on a super long drive and my QLs sort of flare a little bit.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And frankly, a lot of people just, I mean, I used to even get nauseous on Flexeril. But something about Baclofen, I don't even know it's in me at 20 milligrams twice a day, but it actually takes the edge off. And where I typically find this beneficial is is if I slept wrong and I get a kink in my trap, or I've been on a super long drive and my QLs sort of flare a little bit.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And I know that if I had all the time in the world, I could go and stretch my way out of that. But sometimes I just don't have that time and I need to kind of get right back to doing something awful like sitting. And just two or three days of 20 milligrams of baclofen BID with a little NSAID and like, I'm as good as new and I save myself the real flare up.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And I know that if I had all the time in the world, I could go and stretch my way out of that. But sometimes I just don't have that time and I need to kind of get right back to doing something awful like sitting. And just two or three days of 20 milligrams of baclofen BID with a little NSAID and like, I'm as good as new and I save myself the real flare up.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

What are your experience with muscle relaxants?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

What are your experience with muscle relaxants?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

So how many days are you comfortable with a person?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

So how many days are you comfortable with a person?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

What doses typically, or is it just individual?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

What doses typically, or is it just individual?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And what dose are you comfortable up to 20 milligrams three times a day?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And what dose are you comfortable up to 20 milligrams three times a day?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Okay. You alluded to Neurontin earlier, and you alluded to the fact that it played a role in my recovery because once we got the big stuff out of the way, I still had a couple of years of peripheral nerve injury. And the only way to put the fire out in my foot was Neurontin. And unfortunately, initially it required four grams a day. I was taking a gram four times a day or something like that.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

Okay. You alluded to Neurontin earlier, and you alluded to the fact that it played a role in my recovery because once we got the big stuff out of the way, I still had a couple of years of peripheral nerve injury. And the only way to put the fire out in my foot was Neurontin. And unfortunately, initially it required four grams a day. I was taking a gram four times a day or something like that.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And the good news is it worked. The bad news is you're pretty much always tired. So I was very happy over time to get that dose down. And I think within 18 months, I was completely off the Neurontin and lo and behold, never experienced. Although interestingly, maybe once every year, I get like an enormous surge of fire into that same foot.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

And the good news is it worked. The bad news is you're pretty much always tired. So I was very happy over time to get that dose down. And I think within 18 months, I was completely off the Neurontin and lo and behold, never experienced. Although interestingly, maybe once every year, I get like an enormous surge of fire into that same foot.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

literally one shot of flame that lasts seconds and it's gone, but essentially never again. Is Neurontin still a very powerful tool in the use of neuropathic pain? You alluded to other drugs like antidepressants as well, in addition to a rather impotent anti-seizure med, but what else do you have at your disposal for this type of pain?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

literally one shot of flame that lasts seconds and it's gone, but essentially never again. Is Neurontin still a very powerful tool in the use of neuropathic pain? You alluded to other drugs like antidepressants as well, in addition to a rather impotent anti-seizure med, but what else do you have at your disposal for this type of pain?

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

You could fall asleep driving.

The Peter Attia Drive
#345 ‒ Chronic pain: pathways, treatment, and the path to physical and psychological recovery | Sean Mackey, M.D., Ph.D.

You could fall asleep driving.