Dr. Peter Attia

70 kilo person.

70 kilo person.

What are the other areas where LDN is just captivating the world?

What are the other areas where LDN is just captivating the world?

Thalamic pain.

Thalamic pain.

He's tried everything. Let's try low-dose naltrexone. Why does he come to a pain doc? Because he's got terrible pain. Okay, so he wasn't coming to you for the speech issue.

He's tried everything. Let's try low-dose naltrexone. Why does he come to a pain doc? Because he's got terrible pain. Okay, so he wasn't coming to you for the speech issue.

Somehow, if that model makes sense, which it at least teleologically does, something about that inflammatory zone in the middle between what was clearly gone and not is poisoning the part that's still okay. What is the downside of this? Meaning, what would one need to be mindful of in trying an approach like this? The beauty of this

Somehow, if that model makes sense, which it at least teleologically does, something about that inflammatory zone in the middle between what was clearly gone and not is poisoning the part that's still okay. What is the downside of this? Meaning, what would one need to be mindful of in trying an approach like this? The beauty of this

Here's a silly question. Yeah. What's the scenario in which inflammation of the glia is a good thing?

Here's a silly question. Yeah. What's the scenario in which inflammation of the glia is a good thing?

I guess where I'm going with this is we think that at least a subset of people with neurodegenerative diseases, and you mentioned multiple sclerosis, but we think this is true in at least some cases of Alzheimer's disease, that neuroinflammation is a part of the pathology.

I guess where I'm going with this is we think that at least a subset of people with neurodegenerative diseases, and you mentioned multiple sclerosis, but we think this is true in at least some cases of Alzheimer's disease, that neuroinflammation is a part of the pathology.

So would there be any efficacy to a trial there in either an individual with MCI, mild cognitive impairment, or as crazy as this sounds, is there a reason to consider it prophylactically in high-risk individuals? With the caveat that, hey, by the way, if you happen to get an infection, this would be a good time to stop it and ride it out and get better.

So would there be any efficacy to a trial there in either an individual with MCI, mild cognitive impairment, or as crazy as this sounds, is there a reason to consider it prophylactically in high-risk individuals? With the caveat that, hey, by the way, if you happen to get an infection, this would be a good time to stop it and ride it out and get better.

At 10x the dose. How long are they typically on that drug? Lifetime. So meaning for a subset of individuals, just putting them on the party dose of 50 milligrams of naltrexone keeps them free of alcohol and opioids for life because it so blunts the pleasure center.

At 10x the dose. How long are they typically on that drug? Lifetime. So meaning for a subset of individuals, just putting them on the party dose of 50 milligrams of naltrexone keeps them free of alcohol and opioids for life because it so blunts the pleasure center.

You have to want to be off.

You have to want to be off.