Dr. Peter Attia

Can't get low-dose naltrexone there. You mean it has to be compounded at 4.5, you're saying? You're right.

Can't get low-dose naltrexone there. You mean it has to be compounded at 4.5, you're saying? You're right.

So it's basically a free drug.

So it's basically a free drug.

Yeah. I'm very curious to see if anybody has looked at LDN in any of the neuroinflammation stuff. We see the relationship between herpes simplex virus and Alzheimer's disease, between shingles, especially ocular variants of it and Alzheimer's disease. We know that there is some relationship between inflammation and this disease. And we know that that's obviously not all paths cross through that.

Yeah. I'm very curious to see if anybody has looked at LDN in any of the neuroinflammation stuff. We see the relationship between herpes simplex virus and Alzheimer's disease, between shingles, especially ocular variants of it and Alzheimer's disease. We know that there is some relationship between inflammation and this disease. And we know that that's obviously not all paths cross through that.

There are lipid mediated paths, metabolic paths, vascular paths. I think it would be very difficult to make the case there's not an inflammatory path towards that condition. And so interesting to think about.

There are lipid mediated paths, metabolic paths, vascular paths. I think it would be very difficult to make the case there's not an inflammatory path towards that condition. And so interesting to think about.

What's the evidence for the inhibition of the toll-like receptor? Is that in vitro? Yeah, it is in vitro.

What's the evidence for the inhibition of the toll-like receptor? Is that in vitro? Yeah, it is in vitro.

Why do you think you see? I mean, that's an interesting one.

Why do you think you see? I mean, that's an interesting one.

Yeah. So when we met 25 years ago, how big was the department at Stanford in pain?

Yeah. So when we met 25 years ago, how big was the department at Stanford in pain?

I'll finish the story of how we met. So I'm in this state of total hell. In addition to all the stuff I mentioned about this incredible pain, I couldn't even stand up, literally couldn't stand. And if I did, I had to be hunched over. And so at the time I was dating an anesthesiology resident and she was the one that said, hey, we just need to get you in this pain clinic.

I'll finish the story of how we met. So I'm in this state of total hell. In addition to all the stuff I mentioned about this incredible pain, I couldn't even stand up, literally couldn't stand. And if I did, I had to be hunched over. And so at the time I was dating an anesthesiology resident and she was the one that said, hey, we just need to get you in this pain clinic.

We got to break some stuff. This is going nowhere. You're circling the drain here, kid. I think she was in her last year of anesthesiology. So I think she was doing a rotation through pain, maybe. That's probably how she weaseled me in there. So I come and see you in clinic. By the way, at this point, my mom had flown down from Toronto to take care of me.

We got to break some stuff. This is going nowhere. You're circling the drain here, kid. I think she was in her last year of anesthesiology. So I think she was doing a rotation through pain, maybe. That's probably how she weaseled me in there. So I come and see you in clinic. By the way, at this point, my mom had flown down from Toronto to take care of me.

It's not like I could drive or do anything. So my mom drives me into the hospital. Come in and see you. You hear the story. We'd ruled out anything that required any more surgical intervention. In other words, I'd undergone another MRI. I'd had a flexion extension film. I wasn't surgically unstable. And in fact, where the original injury was didn't even seem to be what was driving the pain now.

It's not like I could drive or do anything. So my mom drives me into the hospital. Come in and see you. You hear the story. We'd ruled out anything that required any more surgical intervention. In other words, I'd undergone another MRI. I'd had a flexion extension film. I wasn't surgically unstable. And in fact, where the original injury was didn't even seem to be what was driving the pain now.