Dr. Peter Attia
👤 SpeakerAppearances Over Time
Podcast Appearances
So what I tell people to do is figure out what works best for you because there's some people that just can't do dairy proteins. Remember, just because you can't tolerate dairy doesn't mean you can't tolerate a dairy protein. Most people who can't tolerate dairy can't tolerate the carbohydrate in the dairy, but they're totally fine with the protein. So give it a try.
So what I tell people to do is figure out what works best for you because there's some people that just can't do dairy proteins. Remember, just because you can't tolerate dairy doesn't mean you can't tolerate a dairy protein. Most people who can't tolerate dairy can't tolerate the carbohydrate in the dairy, but they're totally fine with the protein. So give it a try.
Anything else? Yes.
Anything else? Yes.
So you're saying a few years ago, he did a genetic test and it did not show a genetic. Okay. So let's assume that the test was correct. What it was screening for was very likely a gene called the APOE4 gene. And this is a gene, the APOE gene that exists in three types. There's the number two, the number three, and the number four.
So you're saying a few years ago, he did a genetic test and it did not show a genetic. Okay. So let's assume that the test was correct. What it was screening for was very likely a gene called the APOE4 gene. And this is a gene, the APOE gene that exists in three types. There's the number two, the number three, and the number four.
Now, every one of us has two copies of every gene because you got one from your mom and one from your dad. So if there's three types of a gene and there are two copies, there's six combinations. We can go through them all. You could be a 2-2, you could be a 2-3, you could be a 2-4, you could be a 3-3, a 3-4, or a 4-4. Okay, why is that relevant?
Now, every one of us has two copies of every gene because you got one from your mom and one from your dad. So if there's three types of a gene and there are two copies, there's six combinations. We can go through them all. You could be a 2-2, you could be a 2-3, you could be a 2-4, you could be a 3-3, a 3-4, or a 4-4. Okay, why is that relevant?
One of those types is higher risk than the other two, and that's the four. So people who have two copies of the four are at significantly higher risk for Alzheimer's disease, about 10 times higher risk. That doesn't mean that they're guaranteed to get it, but their risk is significantly higher. People who have one copy, typically a three and a four, are at about a two times risk.
One of those types is higher risk than the other two, and that's the four. So people who have two copies of the four are at significantly higher risk for Alzheimer's disease, about 10 times higher risk. That doesn't mean that they're guaranteed to get it, but their risk is significantly higher. People who have one copy, typically a three and a four, are at about a two times risk.
And so what that study told you was, what I'm assuming it said was you did not have a copy of the four gene. So you might be a 3-3, which by the way, most of you probably are. 60% of the population is a 3-3. That's the good news. The bad news is it doesn't mean you're free of risk. Because the only people who can't get Alzheimer's disease are people who don't have brains. I mean, I'm being glib.
And so what that study told you was, what I'm assuming it said was you did not have a copy of the four gene. So you might be a 3-3, which by the way, most of you probably are. 60% of the population is a 3-3. That's the good news. The bad news is it doesn't mean you're free of risk. Because the only people who can't get Alzheimer's disease are people who don't have brains. I mean, I'm being glib.
Everybody with a brain is at risk. And unfortunately, women are at almost twice the risk of men. And we don't have a great understanding of why. There are lots of theories. I won't expand on them now for the sake of time. But this is one of the areas where women are disproportionately affected to men. The other one, by the way, being osteoporosis and falls.
Everybody with a brain is at risk. And unfortunately, women are at almost twice the risk of men. And we don't have a great understanding of why. There are lots of theories. I won't expand on them now for the sake of time. But this is one of the areas where women are disproportionately affected to men. The other one, by the way, being osteoporosis and falls.
So we've touched on both of the areas where women are at higher risk. Of course, men have a higher risk of cardiovascular disease. So the takeaway for me is I'm a 3-3 as well, but I don't rest on it. I act as though I'm high risk, meaning I take all the steps possible.
So we've touched on both of the areas where women are at higher risk. Of course, men have a higher risk of cardiovascular disease. So the takeaway for me is I'm a 3-3 as well, but I don't rest on it. I act as though I'm high risk, meaning I take all the steps possible.
Exercising being the single most important thing we can do to preserve brain health, managing nutrition, sleep, all of the things that I can do.
Exercising being the single most important thing we can do to preserve brain health, managing nutrition, sleep, all of the things that I can do.
Yes.
Yes.