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Dr. Peter Attia

πŸ‘€ Speaker
11186 total appearances

Appearances Over Time

Podcast Appearances

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

But sugar is, pardon me, the bigger driver of cancer from a nutrition perspective is likely the growth signals that are very prevalent with obesity and type 2 diabetes. So it's undoubtedly much more the high levels of insulin than the high levels of glucose that are problematic when you're trying to prevent or minimize cancer risk. Okay. Let's move into dementia.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

But sugar is, pardon me, the bigger driver of cancer from a nutrition perspective is likely the growth signals that are very prevalent with obesity and type 2 diabetes. So it's undoubtedly much more the high levels of insulin than the high levels of glucose that are problematic when you're trying to prevent or minimize cancer risk. Okay. Let's move into dementia.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Well, we can definitely prevent some of it. I don't know that it's entirely preventable, just like I don't think any disease is entirely preventable. The closest of the maiden diseases that I think is... I think, again, I think type 2 diabetes and extreme metabolic disease and heart disease are the most preventable. I think the other two are less so. But we know a bunch of things, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Well, we can definitely prevent some of it. I don't know that it's entirely preventable, just like I don't think any disease is entirely preventable. The closest of the maiden diseases that I think is... I think, again, I think type 2 diabetes and extreme metabolic disease and heart disease are the most preventable. I think the other two are less so. But we know a bunch of things, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Well, we can definitely prevent some of it. I don't know that it's entirely preventable, just like I don't think any disease is entirely preventable. The closest of the maiden diseases that I think is... I think, again, I think type 2 diabetes and extreme metabolic disease and heart disease are the most preventable. I think the other two are less so. But we know a bunch of things, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know that... there are a number of behaviors that really, really reduce your risk of dementia. So you can invert that statement and say that doing a lot of those things helps you prevent dementia, right? So what are those things? So exercise has the most potent effect on reducing the risk of dementia. I mean, it's profound, actually. So there are lots of reasons that that could be the case.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know that... there are a number of behaviors that really, really reduce your risk of dementia. So you can invert that statement and say that doing a lot of those things helps you prevent dementia, right? So what are those things? So exercise has the most potent effect on reducing the risk of dementia. I mean, it's profound, actually. So there are lots of reasons that that could be the case.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know that... there are a number of behaviors that really, really reduce your risk of dementia. So you can invert that statement and say that doing a lot of those things helps you prevent dementia, right? So what are those things? So exercise has the most potent effect on reducing the risk of dementia. I mean, it's profound, actually. So there are lots of reasons that that could be the case.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It could be that when you exercise, your muscles make these hormones called myokines, and that myokines are basically pro-neuron, right? They promote neuronal growth. Exercise produces other... Hormones and proteins. So something called brain natriuretic peptide. Another protein called clotho is made. We have a spike in clotho by about 15% right after we exercise.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It could be that when you exercise, your muscles make these hormones called myokines, and that myokines are basically pro-neuron, right? They promote neuronal growth. Exercise produces other... Hormones and proteins. So something called brain natriuretic peptide. Another protein called clotho is made. We have a spike in clotho by about 15% right after we exercise.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It could be that when you exercise, your muscles make these hormones called myokines, and that myokines are basically pro-neuron, right? They promote neuronal growth. Exercise produces other... Hormones and proteins. So something called brain natriuretic peptide. Another protein called clotho is made. We have a spike in clotho by about 15% right after we exercise.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know very clearly through experiments in everything from mice to monkeys that when you inject people with those proteins, they die. They transiently have an improvement in cognition, and even when you give those things to people or to animals in the early stages of cognitive impairment, it reverses it. So there's a whole bunch of reasons that are profoundly beneficial.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know very clearly through experiments in everything from mice to monkeys that when you inject people with those proteins, they die. They transiently have an improvement in cognition, and even when you give those things to people or to animals in the early stages of cognitive impairment, it reverses it. So there's a whole bunch of reasons that are profoundly beneficial.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

We know very clearly through experiments in everything from mice to monkeys that when you inject people with those proteins, they die. They transiently have an improvement in cognition, and even when you give those things to people or to animals in the early stages of cognitive impairment, it reverses it. So there's a whole bunch of reasons that are profoundly beneficial.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Of course, exercise also plays an amazing role in metabolic health and vascular health, which again are two of the biggest risk factors for dementia, metabolic health and vascular health. We look at other things that can get in the way of brain health is disrupted sleep. So a person who doesn't sleep enough or a person who doesn't get a high enough quality of sleep.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Of course, exercise also plays an amazing role in metabolic health and vascular health, which again are two of the biggest risk factors for dementia, metabolic health and vascular health. We look at other things that can get in the way of brain health is disrupted sleep. So a person who doesn't sleep enough or a person who doesn't get a high enough quality of sleep.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Of course, exercise also plays an amazing role in metabolic health and vascular health, which again are two of the biggest risk factors for dementia, metabolic health and vascular health. We look at other things that can get in the way of brain health is disrupted sleep. So a person who doesn't sleep enough or a person who doesn't get a high enough quality of sleep.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, anything that we can do to improve sleep duration, quality staging, et cetera, it's going to be important. All the things that hurt the heart hurt the brain. So ApoB, blood pressure, smoking, we talked about metabolic health. Those things are bad for the heart. They're bad for the brain.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, anything that we can do to improve sleep duration, quality staging, et cetera, it's going to be important. All the things that hurt the heart hurt the brain. So ApoB, blood pressure, smoking, we talked about metabolic health. Those things are bad for the heart. They're bad for the brain.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, anything that we can do to improve sleep duration, quality staging, et cetera, it's going to be important. All the things that hurt the heart hurt the brain. So ApoB, blood pressure, smoking, we talked about metabolic health. Those things are bad for the heart. They're bad for the brain.