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Dr. Peter Attia

πŸ‘€ Speaker
11186 total appearances

Appearances Over Time

Podcast Appearances

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

But, yeah. That alone should also help your anxiety. I think it did. Marijuana is a very interesting drug where for a high number of people, in the short term, they think it's giving them a reduction of anxiety, but it's actually compounding their anxiety.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I had a woman on my podcast who talked about this at length, and she talked about the number of patients where if she can just get them to stop marijuana for... a month, they're going to start to break the cycle of their anxiety. And of course, there are lots of people who use marijuana quite regularly have zero issues with anxiety.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I had a woman on my podcast who talked about this at length, and she talked about the number of patients where if she can just get them to stop marijuana for... a month, they're going to start to break the cycle of their anxiety. And of course, there are lots of people who use marijuana quite regularly have zero issues with anxiety.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I had a woman on my podcast who talked about this at length, and she talked about the number of patients where if she can just get them to stop marijuana for... a month, they're going to start to break the cycle of their anxiety. And of course, there are lots of people who use marijuana quite regularly have zero issues with anxiety.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, I think like most things in mental health, it's really complicated to understand susceptibility windows. Like, why is it that one person, when they use this drug, something negative happens, another person can use the same drug and actually something quite positive happens? What's the susceptibility of that? We're really in our infancy of understanding these things, to put it mildly.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, I think like most things in mental health, it's really complicated to understand susceptibility windows. Like, why is it that one person, when they use this drug, something negative happens, another person can use the same drug and actually something quite positive happens? What's the susceptibility of that? We're really in our infancy of understanding these things, to put it mildly.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

So again, I think like most things in mental health, it's really complicated to understand susceptibility windows. Like, why is it that one person, when they use this drug, something negative happens, another person can use the same drug and actually something quite positive happens? What's the susceptibility of that? We're really in our infancy of understanding these things, to put it mildly.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Certainly nothing directly. Now, look, you could make some indirect cases. And by the way, I don't include MDMA as a psychedelic because it's technically not a psychedelic. It's an empathogen, so it doesn't distort your perception. But as I'm sure you're aware from interviews you've done, I mean, MDMA is probably the more promising of all of those agents when it comes to treating PTSD.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Certainly nothing directly. Now, look, you could make some indirect cases. And by the way, I don't include MDMA as a psychedelic because it's technically not a psychedelic. It's an empathogen, so it doesn't distort your perception. But as I'm sure you're aware from interviews you've done, I mean, MDMA is probably the more promising of all of those agents when it comes to treating PTSD.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Certainly nothing directly. Now, look, you could make some indirect cases. And by the way, I don't include MDMA as a psychedelic because it's technically not a psychedelic. It's an empathogen, so it doesn't distort your perception. But as I'm sure you're aware from interviews you've done, I mean, MDMA is probably the more promising of all of those agents when it comes to treating PTSD.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

And it would be hard to make a case that if you took an individual who's suffering from PTSD and you freed them from the grip of that through MDMA-guided therapy, that you aren't not just reducing their risk of near-term issues that are associated with PTSD, but also long-term issues, including cognitive decline. So again, I think there could be indirect and adjacent benefits of this.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

And it would be hard to make a case that if you took an individual who's suffering from PTSD and you freed them from the grip of that through MDMA-guided therapy, that you aren't not just reducing their risk of near-term issues that are associated with PTSD, but also long-term issues, including cognitive decline. So again, I think there could be indirect and adjacent benefits of this.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

And it would be hard to make a case that if you took an individual who's suffering from PTSD and you freed them from the grip of that through MDMA-guided therapy, that you aren't not just reducing their risk of near-term issues that are associated with PTSD, but also long-term issues, including cognitive decline. So again, I think there could be indirect and adjacent benefits of this.

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I just think with each psychedelic, as with each drug, you have to know the operating window of the drug, right? So like take something that's really obvious and predictable, like Tylenol. So when was the last time you took Tylenol for a headache or something? It's been a long time. All right. But you know how it works. Your kids get a fever, you give them Tylenol, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I just think with each psychedelic, as with each drug, you have to know the operating window of the drug, right? So like take something that's really obvious and predictable, like Tylenol. So when was the last time you took Tylenol for a headache or something? It's been a long time. All right. But you know how it works. Your kids get a fever, you give them Tylenol, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

I just think with each psychedelic, as with each drug, you have to know the operating window of the drug, right? So like take something that's really obvious and predictable, like Tylenol. So when was the last time you took Tylenol for a headache or something? It's been a long time. All right. But you know how it works. Your kids get a fever, you give them Tylenol, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It has a really predictable operating window. You're like, I'm going to give this to you. You're going to feel better. Can't give you too much or I'll hurt your liver. If I give you too little, you're not going to feel anything. But this is the dose at which it works. Advil. Take an Advil if you pulled a muscle or something. Like super, super predictable. MDMA, pretty predictable drug, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It has a really predictable operating window. You're like, I'm going to give this to you. You're going to feel better. Can't give you too much or I'll hurt your liver. If I give you too little, you're not going to feel anything. But this is the dose at which it works. Advil. Take an Advil if you pulled a muscle or something. Like super, super predictable. MDMA, pretty predictable drug, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

It has a really predictable operating window. You're like, I'm going to give this to you. You're going to feel better. Can't give you too much or I'll hurt your liver. If I give you too little, you're not going to feel anything. But this is the dose at which it works. Advil. Take an Advil if you pulled a muscle or something. Like super, super predictable. MDMA, pretty predictable drug, right?

The Shawn Ryan Show
#181 Peter Attia - The Science of Longevity, Nutrition Myths and Medicine 3.0

Like for most people, somewhere between about 75 milligrams and 125 milligrams is going to produce a remarkably consistent effect. Now you layer that in to the right setting with the right therapist, with the right intention, you start to get amazing clinical results with people. Now, when you start to look at psilocybin, LSD, oh, it starts to become a lot less predictable.