Dr. Peter Attia

But you change them at the same frequency?

But you change them at the same frequency?

Okay, I thought you changed the East ring more frequently, but good to know.

Okay, I thought you changed the East ring more frequently, but good to know.

Why not just swap it every two months?

Why not just swap it every two months?

I'm sure there are a couple of my patients that would actually volunteer to do this where we just do twice a week levels for three months while they're on a product, while they're on a ring and just watch the curve.

I'm sure there are a couple of my patients that would actually volunteer to do this where we just do twice a week levels for three months while they're on a product, while they're on a ring and just watch the curve.

That can get expensive.

That can get expensive.

Very low maintenance and complete solution.

Very low maintenance and complete solution.

Two things I want to talk about on the lab front. We've talked a lot about labs, so I'm not sure if you share our view on this. We are really fastidious about using LC-MS for estradiol. We do not want to use the ELISA-based assays at all. Are you pretty meticulous about that, or do you find that you're just happy checking any estradiol?

Two things I want to talk about on the lab front. We've talked a lot about labs, so I'm not sure if you share our view on this. We are really fastidious about using LC-MS for estradiol. We do not want to use the ELISA-based assays at all. Are you pretty meticulous about that, or do you find that you're just happy checking any estradiol?

So let's maybe make that a PSA for people, both physicians who are out there and patients. We have seen that if you do not use the LCMS assay, which is the very sensitive, the liquid chromatography assays, the results can be meaningless. And I mean truly meaningless. And the reason is that the ELISA-based assays are so susceptible to interference from other molecules.

So let's maybe make that a PSA for people, both physicians who are out there and patients. We have seen that if you do not use the LCMS assay, which is the very sensitive, the liquid chromatography assays, the results can be meaningless. And I mean truly meaningless. And the reason is that the ELISA-based assays are so susceptible to interference from other molecules.

And there are some really known obvious supplements that completely obscure the findings. So biotin, which is in a lot of things, will render a non-LCMS test irrelevant. But I think there are other things that we're just not fully aware of. So it is worth splurging and paying the extra. Maybe it's $5 or $10. It would be the cash price difference on that test.

And there are some really known obvious supplements that completely obscure the findings. So biotin, which is in a lot of things, will render a non-LCMS test irrelevant. But I think there are other things that we're just not fully aware of. So it is worth splurging and paying the extra. Maybe it's $5 or $10. It would be the cash price difference on that test.

But absolutely make sure when testosterone and estradiol are being measured, if you're the physician, you actually have to go through the hoops and make sure you're ordering the LCMS test. And if you're a patient, you should be asking for it.

But absolutely make sure when testosterone and estradiol are being measured, if you're the physician, you actually have to go through the hoops and make sure you're ordering the LCMS test. And if you're a patient, you should be asking for it.