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Dr. Rachel Rubin

👤 Person
698 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I think there's some interesting that I've learned that some people say if you take it with fat or you take it with something to eat, it absorbs better because progesterone is not absorbed very well, which is why we always had synthetic progestins in the first place. And so we're still learning the capabilities of micronized progesterone.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I think there's some interesting that I've learned that some people say if you take it with fat or you take it with something to eat, it absorbs better because progesterone is not absorbed very well, which is why we always had synthetic progestins in the first place. And so we're still learning the capabilities of micronized progesterone.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

But according to most menopause specialists out there, they typically will use 100 milligrams every day or 200 milligrams 12 to 14 days of the month.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

But according to most menopause specialists out there, they typically will use 100 milligrams every day or 200 milligrams 12 to 14 days of the month.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They love you forever. It is so fun to get to see.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They love you forever. It is so fun to get to see.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

No question.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

No question.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can do either. You can say, hey, try taking this vaginally and see if that goes away. See if you're no longer feeling anger or bloated or have irritability. And so vaginally can be an option. We love progestin-coated IUDs. They're great in perimenopause. Why? Because people think that you just lightly dance into menopause. It is like bloody murder hell scene. It can be terrible.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can do either. You can say, hey, try taking this vaginally and see if that goes away. See if you're no longer feeling anger or bloated or have irritability. And so vaginally can be an option. We love progestin-coated IUDs. They're great in perimenopause. Why? Because people think that you just lightly dance into menopause. It is like bloody murder hell scene. It can be terrible.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can bleed the whole month. You can bleed heavy. You can bleed when you're least expecting it. So the IUD is very nice because it will stop bleeding. And so you throw an estrogen patch on and some testosterone, and that's a really great perimenopause plan. And you get birth control. And you get birth control, which is very important.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can bleed the whole month. You can bleed heavy. You can bleed when you're least expecting it. So the IUD is very nice because it will stop bleeding. And so you throw an estrogen patch on and some testosterone, and that's a really great perimenopause plan. And you get birth control. And you get birth control, which is very important.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can add micronized progesterone to the patient who gets good sleep, even if they have an IUD. That doesn't add danger. We love that. So we love IUDs for this population. There's another synthetic progestins, which you can use as well. I've seen people do things like Slind, which is a birth control, a progestin-only birth control pill, add a patch in testosterone to that as well.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

You can add micronized progesterone to the patient who gets good sleep, even if they have an IUD. That doesn't add danger. We love that. So we love IUDs for this population. There's another synthetic progestins, which you can use as well. I've seen people do things like Slind, which is a birth control, a progestin-only birth control pill, add a patch in testosterone to that as well.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Now, again, synthetic progestins sometimes can have mood side effects as well. So they're not completely benign for all people. There's another, I don't know if you've used this at all in your practice, it's called Duave. Have you heard of this? It's an oral estrogen, but it also has what's called basodoxafine, which protects the uterus, but is not a progesterone-based medicine.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Now, again, synthetic progestins sometimes can have mood side effects as well. So they're not completely benign for all people. There's another, I don't know if you've used this at all in your practice, it's called Duave. Have you heard of this? It's an oral estrogen, but it also has what's called basodoxafine, which protects the uterus, but is not a progesterone-based medicine.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I wish they were separate. I wish we could just give basodoxafine alone. Any pharmaceutical reps? so that you don't have to use oral estrogen if you don't have to. Oral estrogen is not evil. I'm a sex doctor, and we know that transdermal is a little better for sexual function. So that's, again, why I'm a big fan of transdermal products as well. But that's kind of another option.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I wish they were separate. I wish we could just give basodoxafine alone. Any pharmaceutical reps? so that you don't have to use oral estrogen if you don't have to. Oral estrogen is not evil. I'm a sex doctor, and we know that transdermal is a little better for sexual function. So that's, again, why I'm a big fan of transdermal products as well. But that's kind of another option.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

People get hysterectomies for lots of reasons. We've had patients do that who really don't tolerate progesterone, and then you can just use estrogen only.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

People get hysterectomies for lots of reasons. We've had patients do that who really don't tolerate progesterone, and then you can just use estrogen only.