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Dr. Rachel Rubin

👤 Person
698 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

It's something my research team's working on is I think I have more patients who never start testosterone therapy because of the fear of side effects than actually stop testosterone therapy because of the side effects. That's my observation in doing a lot of this. Now, when we talk about side effects, I tell them, think about a horny teenager.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

It's something my research team's working on is I think I have more patients who never start testosterone therapy because of the fear of side effects than actually stop testosterone therapy because of the side effects. That's my observation in doing a lot of this. Now, when we talk about side effects, I tell them, think about a horny teenager.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They have these great libidos, but they have some oily skin, acne. But that's when you get really high with your doses. We really don't see it clinically. Yes, I use FDA approved testosterone for men, just a dose is one tenth a dose in a way. They rub it on their leg because if they do get hair on their leg, people are used to having hair on their leg.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

They have these great libidos, but they have some oily skin, acne. But that's when you get really high with your doses. We really don't see it clinically. Yes, I use FDA approved testosterone for men, just a dose is one tenth a dose in a way. They rub it on their leg because if they do get hair on their leg, people are used to having hair on their leg.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And so they shave it, they wax it, they laser it, whatever it is that they do with leg hair. I don't have that many patients stop for acne, oily skin. I think there's that fear when you get really high in the dose. So I'm not a pellet promoter or user because you get super physiologic levels and I can't take it out if you get a pellet put in.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And so they shave it, they wax it, they laser it, whatever it is that they do with leg hair. I don't have that many patients stop for acne, oily skin. I think there's that fear when you get really high in the dose. So I'm not a pellet promoter or user because you get super physiologic levels and I can't take it out if you get a pellet put in.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And so if you have deepening voice or clitoromegaly hair issues, these are the challenges with some of these super physiologic levels. But when we're using reasonably dosed topicals, we really see magic happen.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And so if you have deepening voice or clitoromegaly hair issues, these are the challenges with some of these super physiologic levels. But when we're using reasonably dosed topicals, we really see magic happen.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And I can't tell you, when we get estrogen and progesterone right for our patients, it is by adding that third piece, that testosterone, because your ovary probably does more than three things, but at this point, estrogen, progesterone, and testosterone, when we add that testosterone piece, it's wild. All the patients come back and they say to me, wow, I feel like me again. It's wild.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And I can't tell you, when we get estrogen and progesterone right for our patients, it is by adding that third piece, that testosterone, because your ovary probably does more than three things, but at this point, estrogen, progesterone, and testosterone, when we add that testosterone piece, it's wild. All the patients come back and they say to me, wow, I feel like me again. It's wild.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

That's the piece, wow, I didn't realize how badly I felt. Wow, that was the missing piece. I hear it over and over and over again. I can't not want that for all women. I can't not want to give them that as an option on the menu.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

That's the piece, wow, I didn't realize how badly I felt. Wow, that was the missing piece. I hear it over and over and over again. I can't not want that for all women. I can't not want to give them that as an option on the menu.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Yeah, that's typically how we do it and how our guidelines look at it. So ISWISH, the International Society for the Study of Women's Sexual Health, fabulous organization. You can find any doctor to help you with menopause and sexual health by going to their website. They came out with a really lovely... how-to practice guideline that they took from the Global Consensus.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

Yeah, that's typically how we do it and how our guidelines look at it. So ISWISH, the International Society for the Study of Women's Sexual Health, fabulous organization. You can find any doctor to help you with menopause and sexual health by going to their website. They came out with a really lovely... how-to practice guideline that they took from the Global Consensus.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And they do recommend using that FDA-approved testosterone for men and using it at appropriately doses for females. So I like Testim, which is sort of the 1% generic testosterone gel. I'll show it to you. I brought it for you to show you. It's a five milliliter tube of gel. Our male patients would use the whole tube of gel, rub it on their chest every day.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

And they do recommend using that FDA-approved testosterone for men and using it at appropriately doses for females. So I like Testim, which is sort of the 1% generic testosterone gel. I'll show it to you. I brought it for you to show you. It's a five milliliter tube of gel. Our male patients would use the whole tube of gel, rub it on their chest every day.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I have very few men who do that, by the way. Injections, orals, those are much better. And so I tell my patients, use a blob or a 0.5 ml so they can put it in a syringe if they want to and dose out that 0.5 ml. They take a blob. They rub it on their calf every day. And so just don't use the whole tube should last you about a week or 10 days. It's an ish.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

I have very few men who do that, by the way. Injections, orals, those are much better. And so I tell my patients, use a blob or a 0.5 ml so they can put it in a syringe if they want to and dose out that 0.5 ml. They take a blob. They rub it on their calf every day. And so just don't use the whole tube should last you about a week or 10 days. It's an ish.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

It's not an exact precision science, but the patients can figure this out. It's not that challenging. I will say this, and I think I have colleagues who disagree with me on this, and I would love to know your experience. I think testosterone, I think for men too, but that's my bias, it takes a while to kick in.

The Peter Attia Drive
#348 ‒ Women’s sexual health, menopause, and hormone replacement therapy (HRT) | Rachel Rubin, M.D.

It's not an exact precision science, but the patients can figure this out. It's not that challenging. I will say this, and I think I have colleagues who disagree with me on this, and I would love to know your experience. I think testosterone, I think for men too, but that's my bias, it takes a while to kick in.