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Dr. Rhonda Patrick

๐Ÿ‘ค Speaker
6660 total appearances

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Podcast Appearances

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

And this is a pathway that regulates a lot of genes and a lot of genes that are related to like glutathione production, genes that are involved in detoxifying compounds that we're exposed to from our food, like heterocyclic amines.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

In fact, there have been GWAS studies.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

So these are genetically, these are studies that are

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

genome-wide associated studies for people listening that aren't familiar.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

People have a variety of versions of genes.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

And we have a gene that's able to make heterocyclic amines to basically detoxify it so it's not as harmful.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

And people that don't have a certain version of that that's doing it well are very prone to like colon cancer and increased cancer risk.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

But if they eat a lot of broccoli and cruciferous vegetables, it negates that risk because they're getting sulforaphane, which activates glutathione transferase and synthase genes.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

So glutathione is a major antioxidant in our brain and in our vascular system and our body, basically.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

There's evidence eating things like, you know,

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

compounds that are like sulforaphane or broccoli or broccoli spouts, which have like a hundred, up to a hundred times more sulforaphane than broccoli are activating glutathione in the brain.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

There's human evidence of that.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

So you do somewhat lower the sulforaphane levels when you cook the broccoli.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

However, there was a study a few years back that showed adding one gram of mustard seed powder ground to your cooked broccoli increases the sulforaphane by fourfold.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

Well, I had shifted to supplementation with sulforaphane.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

There's another compound and it's actually called Moringa.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

It's like a cousin and it activates the NRF2 pathway similarly to sulforaphane.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

And so I've been buying this Cooley Cooley Moringa powder and I add it to my smoothies.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

Omega-3, the marine omega-3 fatty acids.

Huberman Lab
Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

So these are found in marine types of, you know, animals, fish, cold water fish, fatty fish.