Dr. Rhonda Patrick

But also there's a lot of endorphins that are released that make you feel better.

And there's also some evidence that like doing that hard thing when you're uncomfortable, when you're exercising hard or working out hard, or even doing a sauna, when you're sitting in the sauna, it's hot and you're uncomfortable because sauna does mimic moderate intensity exercise.

Those things are – that uncomfortableness is your brain's endogenous opioid system that is being activated.

And you're making something called dynorphin.

This is the opposite of endorphin.

Endorphin is the feel-good opioid.

Dynorphin is the thing that's uncomfortable where you're like, oh, this sucks.

I hate it, right?

There's a neuropeptide being made called dynorphin.

And guess what?

When you make that dynorphin, there's an adaptation that happens.

That adaptation is your brain going – Commonly known as –

Not dimorphine.

Dinorphin.

You're confusing the audience.

D-I-A-N-O-R-P-H-I-N.

Dinorphin.

So.

Yes.

So what happens is it's binding to a kappa opioid.