Dr. Richard Johnson
👤 PersonAppearances Over Time
Podcast Appearances
Whereas all the areas that tryptophan inhibits turn out to be the regions of the brain that are specifically targeted in Alzheimer's. I mean, eventually Alzheimer's will affect all the brain, but in the beginning, you can really show this difference. And so when I presented that to Dale and to David Perlmutter, they go,
Whereas all the areas that tryptophan inhibits turn out to be the regions of the brain that are specifically targeted in Alzheimer's. I mean, eventually Alzheimer's will affect all the brain, but in the beginning, you can really show this difference. And so when I presented that to Dale and to David Perlmutter, they go,
You know, this is pretty significant because not so many people have been able to explain why Alzheimer's affects one region and not another.
You know, this is pretty significant because not so many people have been able to explain why Alzheimer's affects one region and not another.
You know, this is pretty significant because not so many people have been able to explain why Alzheimer's affects one region and not another.
Yeah. So so yes. So to summarize how we think of this or the way I think of this, and I have to again thank David Perlmutter and Dale Bredesen and Maria Nagel. And but what we think is going on or is that, you know, fructose developed as an evolutionary mechanism to help animals survive. Fructose is the nutrient that helps you store energy, and it's meant to help you.
Yeah. So so yes. So to summarize how we think of this or the way I think of this, and I have to again thank David Perlmutter and Dale Bredesen and Maria Nagel. And but what we think is going on or is that, you know, fructose developed as an evolutionary mechanism to help animals survive. Fructose is the nutrient that helps you store energy, and it's meant to help you.
Yeah. So so yes. So to summarize how we think of this or the way I think of this, and I have to again thank David Perlmutter and Dale Bredesen and Maria Nagel. And but what we think is going on or is that, you know, fructose developed as an evolutionary mechanism to help animals survive. Fructose is the nutrient that helps you store energy, and it's meant to help you.
It was meant to be a good thing. When there's very little food coming, you want to eat fructose to store that fat. You want to stimulate foraging so you can get the food so you can survive. It's all meant to be short-term and to be beneficial. But what's happened is we developed taste for foods that could make fruit dust, right? We develop sweet taste so we can pick out that food.
It was meant to be a good thing. When there's very little food coming, you want to eat fructose to store that fat. You want to stimulate foraging so you can get the food so you can survive. It's all meant to be short-term and to be beneficial. But what's happened is we developed taste for foods that could make fruit dust, right? We develop sweet taste so we can pick out that food.
It was meant to be a good thing. When there's very little food coming, you want to eat fructose to store that fat. You want to stimulate foraging so you can get the food so you can survive. It's all meant to be short-term and to be beneficial. But what's happened is we developed taste for foods that could make fruit dust, right? We develop sweet taste so we can pick out that food.
We salt taste so that we can pick out the foods that that tend to help put fat on us. And in a world of hunter gatherers and in a world where where food wasn't so easily available, these were beneficial, you know, and if you, you know, and then
We salt taste so that we can pick out the foods that that tend to help put fat on us. And in a world of hunter gatherers and in a world where where food wasn't so easily available, these were beneficial, you know, and if you, you know, and then
We salt taste so that we can pick out the foods that that tend to help put fat on us. And in a world of hunter gatherers and in a world where where food wasn't so easily available, these were beneficial, you know, and if you, you know, and then
You know, now that we have all this high fructose corn syrup and sugary foods and processed foods injected with salt and sugar and we have, you know, and now that we can go to the grocery store whenever we want and we learn to crave sugar and then we, you know, we develop a craving and some people crave salty foods and we're eating all these foods to stimulate this foraging and all this.
You know, now that we have all this high fructose corn syrup and sugary foods and processed foods injected with salt and sugar and we have, you know, and now that we can go to the grocery store whenever we want and we learn to crave sugar and then we, you know, we develop a craving and some people crave salty foods and we're eating all these foods to stimulate this foraging and all this.
You know, now that we have all this high fructose corn syrup and sugary foods and processed foods injected with salt and sugar and we have, you know, and now that we can go to the grocery store whenever we want and we learn to crave sugar and then we, you know, we develop a craving and some people crave salty foods and we're eating all these foods to stimulate this foraging and all this.
And what's happening is we're reducing the ATP, the energy in these cells, you know, in our brain, in our muscle, and it's leading to muscle wasting, sarcopenia. It's leading to, you know, as we lose our energy in the brain, as the cells get less ATP, They can't function as well. And then what happens is they start dying and they get inflamed and they start creating these amyloid plaques.
And what's happening is we're reducing the ATP, the energy in these cells, you know, in our brain, in our muscle, and it's leading to muscle wasting, sarcopenia. It's leading to, you know, as we lose our energy in the brain, as the cells get less ATP, They can't function as well. And then what happens is they start dying and they get inflamed and they start creating these amyloid plaques.
And what's happening is we're reducing the ATP, the energy in these cells, you know, in our brain, in our muscle, and it's leading to muscle wasting, sarcopenia. It's leading to, you know, as we lose our energy in the brain, as the cells get less ATP, They can't function as well. And then what happens is they start dying and they get inflamed and they start creating these amyloid plaques.