BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
Yeah, I think that all makes sense.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
I mean, I think what you said about MRI specifically is an important point.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
You know, often we will, I'd say nearly 100% of the time, I'll do an MRI before my confirmatory biopsy for obvious reasons.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
But a lot of times, I'm sure as in your clinic, I might be seeing a patient who's been diagnosed elsewhere and
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
And I don't have the MRI reviewed by our specialized radiologists, which we know can change the read.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
But I think it's a good point to remind ourselves that we really shouldn't be doing it more than every 12 to 24 months after the initial confirmatory biopsy.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
What about your triggers for intervention?
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
I mean, you touched on this briefly, and I know that there's not great consensus in the guidelines in terms of what we're looking for.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
But practically in your clinic, what do you generally use to guide that decision?
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
Yeah.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
And you bring up one point that I don't think we covered earlier.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
So I'll just go back and ask you that now.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
Introductal obviously would upgrade the patient automatically.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
But for you, is crib reform morphology an automatic disqualifier at the initial biopsy?
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
Got it.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
Now, similar to all these other tools that we use to guide our decision making in terms of frequency of biopsies.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
intensification of surveillance, et cetera, we're seeing more and more genomic testing products enter the market.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
And a lot of those genomic tests
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
kind of market themselves with a value proposition that like this specific clinical scenario, intermediate risk prostate cancer, high volume, low risk prostate cancer, you know, this is how they really help answer those tough management questions.
BackTable Urology
Ep. 288 Active Surveillance for Intermediate Risk Prostate Cancer with Dr. Claire de la Calle
So I would love to hear your thoughts on how genomic testing fits into this puzzle, because as we've covered, it's not really a slam dunk answer.