Dr. Sabine Hazan

Thank you. Thank you. Thank you for having me.

Thank you. Thank you. Thank you for having me.

Progena Biome because it's from your genes to your biome. Progena.

Progena Biome because it's from your genes to your biome. Progena.

So we're a research genetic sequencing lab. As you know, during the pandemic, we kind of made our debut by finding COVID in the stools. And then from there, we isolated a bacteria that we believe protects you from COVID or viruses. And then from there discovered kind of the microbiome. So that's the purpose of the company is really to research the microbiome and disease.

So we're a research genetic sequencing lab. As you know, during the pandemic, we kind of made our debut by finding COVID in the stools. And then from there, we isolated a bacteria that we believe protects you from COVID or viruses. And then from there discovered kind of the microbiome. So that's the purpose of the company is really to research the microbiome and disease.

And we have 61 clinical trials going on on the microbiome and disease right now.

And we have 61 clinical trials going on on the microbiome and disease right now.

No, I started the company a couple of years prior because I was interested in the microbiome. I was seeing something when I was doing fecal transplant, the process of taking stools from healthy donors and putting it into unhealthy with C. diff. And what happened was I was really interested in...

No, I started the company a couple of years prior because I was interested in the microbiome. I was seeing something when I was doing fecal transplant, the process of taking stools from healthy donors and putting it into unhealthy with C. diff. And what happened was I was really interested in...

You know, I had a case of a patient with Alzheimer's who improved after fecal transplant or intestinal microbiota transplant. And I said, what happened there? What microbe causes Alzheimer's or what group of microbes or what signature microbiome is involved in Alzheimer's?

You know, I had a case of a patient with Alzheimer's who improved after fecal transplant or intestinal microbiota transplant. And I said, what happened there? What microbe causes Alzheimer's or what group of microbes or what signature microbiome is involved in Alzheimer's?

So rather than just bringing a stool product to market and a pharma product, I was more interested into the microbe itself, the relationship of microbes and how does disease occur? We all know disease begins in the gut, but I just didn't know how and why and which microbes are involved. So I founded ProgenaBiome with that concept.

So rather than just bringing a stool product to market and a pharma product, I was more interested into the microbe itself, the relationship of microbes and how does disease occur? We all know disease begins in the gut, but I just didn't know how and why and which microbes are involved. So I founded ProgenaBiome with that concept.

Correct. I knew because I saw something changed with C. diff. My first case was a doctor actually that was dying. And I was the girl that was doing clinical trials for C. diff. So when the clinical trial didn't work, And the pharmaceutical product, first of all, vancomycin, flagyl didn't work. And then I went the clinical trial route.

Correct. I knew because I saw something changed with C. diff. My first case was a doctor actually that was dying. And I was the girl that was doing clinical trials for C. diff. So when the clinical trial didn't work, And the pharmaceutical product, first of all, vancomycin, flagyl didn't work. And then I went the clinical trial route.

When the clinical trial route didn't work, I was kind of, I'm not going to let this guy die. So let me try fecal transplant. Everybody's talking about it. And when I saw the colon completely, you know, with ulcerations and mucus and everything, and then... Two weeks later, the colonic mucosa is completely normal. I said, what did that? How did that happen, right?

When the clinical trial route didn't work, I was kind of, I'm not going to let this guy die. So let me try fecal transplant. Everybody's talking about it. And when I saw the colon completely, you know, with ulcerations and mucus and everything, and then... Two weeks later, the colonic mucosa is completely normal. I said, what did that? How did that happen, right?

And so that's basically what got me into asking the question, how did poop change a colon that has a bunch of ulcers to a normal colonic mucosa?

And so that's basically what got me into asking the question, how did poop change a colon that has a bunch of ulcers to a normal colonic mucosa?