Dr. Sagen Zac-Varghese

F-R-A-X.

Yeah, it was developed by the University of Sheffield in 2008.

It has millions of hits every year and used worldwide.

You put the country where you're in and it tells you your risk of fracture.

And that prompted me to ask my mum to ask her GP to get a DEXA scan.

So yeah, it is super helpful.

I think calcium is interesting because I think it's interesting in itself, but I think the hormones that regulate calcium are super interesting in terms of how strongly they defend it.

And I love stories and the stories of the prehistoric animals and how we've evolved.

Well, okay.

So what I find really interesting is if you lie in bed and you don't do anything, you lose bone.

If you're immobile, you lose bone.

So poor astronauts in space lose about 1% of bone mass per month.

As opposed to us who lose about 1% per year.

So you need that gravity going through you.

And the thing about bears that I don't understand enough about that is fascinating is that they can hibernate for months, even up to six months, and they don't get osteoporosis.

They don't lose their bone mass.

Yeah, so I was looking it up because I was thinking, why don't bears get osteoporosis?

And it's something to do, it's really interesting, something to do with parathyroid hormone, but it's also connected to something called CART, which is something that I learned about when I was doing obesity research, which is involved in your obesity and your weight metabolism.

So bears really have got smart physiology.

So I think if we could learn a bit more about bears, that would be useful.