Dr. Scott Sherr
๐ค PersonAppearances Over Time
Podcast Appearances
Whether you take it orally as a trochee, you swallow it, or even obviously in an IV. IV is going to be 100% bioavailable, no doubt about it. But It stays active even when it goes through the liver in first pass metabolism. And most things get deactivated on some level. I always give the example of N-acetylcysteine or NAC. NAC is about 10% bioavailable. So if you take 100 milligrams of NAC,
Whether you take it orally as a trochee, you swallow it, or even obviously in an IV. IV is going to be 100% bioavailable, no doubt about it. But It stays active even when it goes through the liver in first pass metabolism. And most things get deactivated on some level. I always give the example of N-acetylcysteine or NAC. NAC is about 10% bioavailable. So if you take 100 milligrams of NAC,
only 10 milligrams is actually getting into the body. But if you take 16 milligrams of methylene blue, just about 16 milligrams is actually getting into the body. Now, what's different is how fast.
only 10 milligrams is actually getting into the body. But if you take 16 milligrams of methylene blue, just about 16 milligrams is actually getting into the body. Now, what's different is how fast.
Obviously, IV is going to be your fastest, and that's a good thing depending on the system or the issue with methylene blue, but it also can be the most dangerous because it's going to go to the brain the fastest, and we can talk about that. And then a trochee is going to be second fastest because a trochee is going to be dissolving directly into the mucosa of the mouth.
Obviously, IV is going to be your fastest, and that's a good thing depending on the system or the issue with methylene blue, but it also can be the most dangerous because it's going to go to the brain the fastest, and we can talk about that. And then a trochee is going to be second fastest because a trochee is going to be dissolving directly into the mucosa of the mouth.
And that's going to be faster than going through digestion. And obviously swallowing it is going to be slower. Now you asked about food. Now, if you have food in your stomach, when you take methylene blue, it's going to get dissolved much slower overall. So your peak is going to be lower as far as your peak concentration in the blood. Got it.
And that's going to be faster than going through digestion. And obviously swallowing it is going to be slower. Now you asked about food. Now, if you have food in your stomach, when you take methylene blue, it's going to get dissolved much slower overall. So your peak is going to be lower as far as your peak concentration in the blood. Got it.
What I typically recommend is if you're going to swallow methylene blue, It's a swallow on an empty stomach. And then you can eat about 15 or 20 minutes later and help it kind of push it through a little bit faster. But that's usually the best way to do it.
What I typically recommend is if you're going to swallow methylene blue, It's a swallow on an empty stomach. And then you can eat about 15 or 20 minutes later and help it kind of push it through a little bit faster. But that's usually the best way to do it.
I appreciate the perspective because you've been doing this such a long time and you've been playing around with things that are much more tricky than I have over the years with all the peptides and things like that. And it's not safe. If you get more than you need... Methylene blue at higher doses can cause more detox symptoms. It can cause more stress on the mitochondria, as I mentioned.
I appreciate the perspective because you've been doing this such a long time and you've been playing around with things that are much more tricky than I have over the years with all the peptides and things like that. And it's not safe. If you get more than you need... Methylene blue at higher doses can cause more detox symptoms. It can cause more stress on the mitochondria, as I mentioned.
And if you think you're taking 20 milligrams a day, but you're really taking 100 or something like that, that's kind of an extreme example. But once you get to about 80 or so milligrams of methylene, 8,200 milligrams of methylene blue per day, you start building it up in the system. You don't fully...
And if you think you're taking 20 milligrams a day, but you're really taking 100 or something like that, that's kind of an extreme example. But once you get to about 80 or so milligrams of methylene, 8,200 milligrams of methylene blue per day, you start building it up in the system. You don't fully...
detox you don't feel like get rid of it like in your urine in about within about 24 hours and so if you're taking more than that on a regular basis you can get in trouble and so my usual recommendation is you're taking more than about 30 to 40 milligrams a day of methylene blue you really need to be taking at least one day off a week and if you're taking more than that a day
detox you don't feel like get rid of it like in your urine in about within about 24 hours and so if you're taking more than that on a regular basis you can get in trouble and so my usual recommendation is you're taking more than about 30 to 40 milligrams a day of methylene blue you really need to be taking at least one day off a week and if you're taking more than that a day
then thinking about taking more days off per week to make sure you don't have the buildup in the system overall. And so I worry about the liquid because I don't know what people are getting. And people always ask me, what's the best liquid? What's the best liquid? We just haven't found one that I truly trust. And I know what we're doing. I'm supervising with Dr. Ted and the physicians on my team.
then thinking about taking more days off per week to make sure you don't have the buildup in the system overall. And so I worry about the liquid because I don't know what people are getting. And people always ask me, what's the best liquid? What's the best liquid? We just haven't found one that I truly trust. And I know what we're doing. I'm supervising with Dr. Ted and the physicians on my team.
We're supervising the whole process and looking at the C of A's. And then we're always in communication with our labs and our contract manufacturers that are making the products.
We're supervising the whole process and looking at the C of A's. And then we're always in communication with our labs and our contract manufacturers that are making the products.