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Dr. Scott Sherr

๐Ÿ‘ค Speaker
1516 total appearances

Appearances Over Time

Podcast Appearances

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

bring in a new perspective. And that's actually, it's a very important perspective. And one that I think is very impactful is just to remind people that they are not their thoughts, that thoughts are happening in their mind, but there's some other part of their brain that's not having those thoughts at the same time.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So if they're having another part of their brain not have those thoughts at the same time, then they can't be those thoughts. There's something else that they have to be if they can observe those thoughts and observe the part of their brain that's not having those thoughts at the same time. And it's like this, it's like sort of meditation ninja in some ways.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So if they're having another part of their brain not have those thoughts at the same time, then they can't be those thoughts. There's something else that they have to be if they can observe those thoughts and observe the part of their brain that's not having those thoughts at the same time. And it's like this, it's like sort of meditation ninja in some ways.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So if they're having another part of their brain not have those thoughts at the same time, then they can't be those thoughts. There's something else that they have to be if they can observe those thoughts and observe the part of their brain that's not having those thoughts at the same time. And it's like this, it's like sort of meditation ninja in some ways.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It's like in a sense of trying to, but that's really difficult and really difficult in people that are so down or so anxious, right? So that's why like enhancing the GABA system, it's like turning off anxiety or shutting it down 50% can be huge to have this kind of conversation. So I think it very much plays into all of them.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It's like in a sense of trying to, but that's really difficult and really difficult in people that are so down or so anxious, right? So that's why like enhancing the GABA system, it's like turning off anxiety or shutting it down 50% can be huge to have this kind of conversation. So I think it very much plays into all of them.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It's like in a sense of trying to, but that's really difficult and really difficult in people that are so down or so anxious, right? So that's why like enhancing the GABA system, it's like turning off anxiety or shutting it down 50% can be huge to have this kind of conversation. So I think it very much plays into all of them.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So when it comes to epilepsy specifically, GABA regulates the flow of information within neurons and neural networks. And so what happens with epilepsy is that there is an overabundance of this other neurotransmitter that's always in a balance with GABA. So it's called glutamate. So glutamate is your primary excitatory neurotransmitter. And GABA is your primary inhibitory neurotransmitter.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So when it comes to epilepsy specifically, GABA regulates the flow of information within neurons and neural networks. And so what happens with epilepsy is that there is an overabundance of this other neurotransmitter that's always in a balance with GABA. So it's called glutamate. So glutamate is your primary excitatory neurotransmitter. And GABA is your primary inhibitory neurotransmitter.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

So when it comes to epilepsy specifically, GABA regulates the flow of information within neurons and neural networks. And so what happens with epilepsy is that there is an overabundance of this other neurotransmitter that's always in a balance with GABA. So it's called glutamate. So glutamate is your primary excitatory neurotransmitter. And GABA is your primary inhibitory neurotransmitter.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

And they're always in a balance. And in fact, glutamate actually turns in to GABA in the brain. There's very little GABA outside of your brain itself. And so glutamate, again, your excitatory neurotransmitter has to be in balance and actually convert into GABA in the brain. You need two cofactors to be able to do this, magnesium and vitamin B6. So if you're magnesium deficient,

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

And they're always in a balance. And in fact, glutamate actually turns in to GABA in the brain. There's very little GABA outside of your brain itself. And so glutamate, again, your excitatory neurotransmitter has to be in balance and actually convert into GABA in the brain. You need two cofactors to be able to do this, magnesium and vitamin B6. So if you're magnesium deficient,

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

And they're always in a balance. And in fact, glutamate actually turns in to GABA in the brain. There's very little GABA outside of your brain itself. And so glutamate, again, your excitatory neurotransmitter has to be in balance and actually convert into GABA in the brain. You need two cofactors to be able to do this, magnesium and vitamin B6. So if you're magnesium deficient,

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

you're gonna have a hard time converting. If you are B6 deficient, you're also gonna have a hard time converting that glutamate to GABA. So what happens in epilepsy and a lot of these other conditions as well is that you have an overabundance of this glutamate. And so glutamate is excitatory. It makes you feel on, it makes you feel connected.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

you're gonna have a hard time converting. If you are B6 deficient, you're also gonna have a hard time converting that glutamate to GABA. So what happens in epilepsy and a lot of these other conditions as well is that you have an overabundance of this glutamate. And so glutamate is excitatory. It makes you feel on, it makes you feel connected.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

you're gonna have a hard time converting. If you are B6 deficient, you're also gonna have a hard time converting that glutamate to GABA. So what happens in epilepsy and a lot of these other conditions as well is that you have an overabundance of this glutamate. And so glutamate is excitatory. It makes you feel on, it makes you feel connected.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It makes you feel like you have control of like your executive function. You can think and think clearly and think fast. And the problem also though, but if you have too much, glutamate causes excitotoxicity, causes too much excitability in the brain, it can cause seizures. So one of the main reasons why people have seizures is as a glutamate toxicity and a glutamate overload.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It makes you feel like you have control of like your executive function. You can think and think clearly and think fast. And the problem also though, but if you have too much, glutamate causes excitotoxicity, causes too much excitability in the brain, it can cause seizures. So one of the main reasons why people have seizures is as a glutamate toxicity and a glutamate overload.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

It makes you feel like you have control of like your executive function. You can think and think clearly and think fast. And the problem also though, but if you have too much, glutamate causes excitotoxicity, causes too much excitability in the brain, it can cause seizures. So one of the main reasons why people have seizures is as a glutamate toxicity and a glutamate overload.

Passion Struck with John R. Miles
Dr. Scott Sherr on GABA: The Unsung Hero of Brain Health and Stress Resilience | EP 575

And getting more GABA involved can be very effective here. And this is why a lot of the drugs that are involved in treating epilepsy are working on the GABA receptors themselves things like gabapentin for example which is a drug that works on the GABA receptors in a pretty novel way and actually we don't really understand exactly how that drug particularly works but that's an example of that