Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

Dr. Sergiu Pașcă

👤 Speaker
1146 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We can make parts of the nervous system.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We can put them in various combinations.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But we've never made an entire brain.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Actually, I don't know of any scientist who has as a goal to try to build the entire nervous system as an exact replica of the brain.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So I think...

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

The words matter a lot.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And in fact, that has been one of the things that we've done over the years.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

A few years ago, I thought it would be really important to get most of the scientists in the field together and start thinking about these terms really carefully.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And so we got together, created sort of like an ad hoc consortium, and through many, many calls, one-on-one in various groups, we came up with one paper which was published in Nature a couple of years ago, which really comes as a nomenclature for the field.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We as scientists decided this are sort of like the way we classify them.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

These are the terms that we all agreed should be used and not use, not, for instance, you know, project, let's say,

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

complex terms onto this.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We'll never say that an organoid like C's just because there's a retina, right?

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We'll never say that a cortical organoid has intelligence because that's a property of an entire nervous system.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So we think that this is actually quite important, especially in communicating with the public.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And that consortium turned out to be an actually great exercise of getting everybody together and now thinking what are some of the common practices that we should all use when we report this experiment.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So we just had a few months ago another paper that came also as a perspective in science, in nature, where we also laid out the framework for the field.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

I think this also speaks to the fact that we're entering a new era in science

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Where I think, you know, you would say all these labs are working separately.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

They're competing with each other.