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Dr. Spencer Nadolsky

👤 Speaker
351 total appearances

Appearances Over Time

Podcast Appearances

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yeah. So we're publishing some case studies where we have a prospective trial or I should say a prospective study, not a trial. We're not doing a randomized trial. First, we actually will be doing a randomized trial, but we're showing minimal fat-free mass loss. So For people listening, you can follow my chief science officer, Dr. Grant Tinsley, who's a big-time body composition expert.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yeah. So we're publishing some case studies where we have a prospective trial or I should say a prospective study, not a trial. We're not doing a randomized trial. First, we actually will be doing a randomized trial, but we're showing minimal fat-free mass loss. So For people listening, you can follow my chief science officer, Dr. Grant Tinsley, who's a big-time body composition expert.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But he goes into how DEXA scans don't look at muscle directly, but it's a fat-free mass loss. And when people lift weights and eat adequate amounts of protein, not even overdoing it, but lifting weights, it's minimal. It's minimal. It's 10% or less or sometimes zero or even they gain fat-free mass. It's amazing.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But he goes into how DEXA scans don't look at muscle directly, but it's a fat-free mass loss. And when people lift weights and eat adequate amounts of protein, not even overdoing it, but lifting weights, it's minimal. It's minimal. It's 10% or less or sometimes zero or even they gain fat-free mass. It's amazing.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But he goes into how DEXA scans don't look at muscle directly, but it's a fat-free mass loss. And when people lift weights and eat adequate amounts of protein, not even overdoing it, but lifting weights, it's minimal. It's minimal. It's 10% or less or sometimes zero or even they gain fat-free mass. It's amazing.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yes, by far.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yes, by far.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yes, by far.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yeah, because this is like kind of standard sports medicine literature where the bodybuilders, the athletes... And when you look at that data, you need to send the signal to the muscle. You can give the muscle building blocks, but if you don't have the signal to build, it's not going to build anymore. It can maybe a little bit.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yeah, because this is like kind of standard sports medicine literature where the bodybuilders, the athletes... And when you look at that data, you need to send the signal to the muscle. You can give the muscle building blocks, but if you don't have the signal to build, it's not going to build anymore. It can maybe a little bit.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

Yeah, because this is like kind of standard sports medicine literature where the bodybuilders, the athletes... And when you look at that data, you need to send the signal to the muscle. You can give the muscle building blocks, but if you don't have the signal to build, it's not going to build anymore. It can maybe a little bit.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But if you're not sending that signal to the muscle to grow or even just stick around, it's gone. So its magnitude is higher of importance now. And if anybody wants, so people like Brad Schoenfeld, Stu Phillips, those guys are kind of pioneers in that stuff. But it actually crosses over to obesity with these medicines. Actually, I was at an obesity conference and we did a debate.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But if you're not sending that signal to the muscle to grow or even just stick around, it's gone. So its magnitude is higher of importance now. And if anybody wants, so people like Brad Schoenfeld, Stu Phillips, those guys are kind of pioneers in that stuff. But it actually crosses over to obesity with these medicines. Actually, I was at an obesity conference and we did a debate.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

But if you're not sending that signal to the muscle to grow or even just stick around, it's gone. So its magnitude is higher of importance now. And if anybody wants, so people like Brad Schoenfeld, Stu Phillips, those guys are kind of pioneers in that stuff. But it actually crosses over to obesity with these medicines. Actually, I was at an obesity conference and we did a debate.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

I was going against a guy, John Jakisek, brilliant exercise researcher. And we had to pick sides of resistance training versus aerobic training when it comes to obesity. And back then, it was 2022 or 2023. Yeah, 2022 it was. Had to have been. Yeah, 2022 maybe. And I picked resistance training, of course. And I went through all of it.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

I was going against a guy, John Jakisek, brilliant exercise researcher. And we had to pick sides of resistance training versus aerobic training when it comes to obesity. And back then, it was 2022 or 2023. Yeah, 2022 it was. Had to have been. Yeah, 2022 maybe. And I picked resistance training, of course. And I went through all of it.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

I was going against a guy, John Jakisek, brilliant exercise researcher. And we had to pick sides of resistance training versus aerobic training when it comes to obesity. And back then, it was 2022 or 2023. Yeah, 2022 it was. Had to have been. Yeah, 2022 maybe. And I picked resistance training, of course. And I went through all of it.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

And back then, these drugs were just kind of coming out and people weren't talking about it as much. But I made the argument that like, look, these medicines will get people walking around and being physical activity. Nothing can replace resistance training. You just can't, you can't replace it with anything. You have to do it. You can't take more protein just to try to make up for it.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

And back then, these drugs were just kind of coming out and people weren't talking about it as much. But I made the argument that like, look, these medicines will get people walking around and being physical activity. Nothing can replace resistance training. You just can't, you can't replace it with anything. You have to do it. You can't take more protein just to try to make up for it.

The Dr. Tyna Show
Obesity Isn’t A Willpower Problem: The Role Of GLP-1s | Dr. Spencer Nadolsky

And back then, these drugs were just kind of coming out and people weren't talking about it as much. But I made the argument that like, look, these medicines will get people walking around and being physical activity. Nothing can replace resistance training. You just can't, you can't replace it with anything. You have to do it. You can't take more protein just to try to make up for it.