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Dr. Stacy Sims

πŸ‘€ Speaker
3375 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So when we're looking at that obesogenic outcome, the actual timing hasn't been tested yet. to see how can we expand or contract that eating window for men. But for women, because of that cortisol peak right after waking up, women tend to be already sympathetically driven. So then they walk around more tired but wired.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

and have a really, really difficult time accessing any kind of parasympathetic responses down the way. Where if you have something really small where you're bringing blood sugar up, then it's signaling to the hypothalamus, hey, yeah, there's some nutrition on board, then we can start our day.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

and have a really, really difficult time accessing any kind of parasympathetic responses down the way. Where if you have something really small where you're bringing blood sugar up, then it's signaling to the hypothalamus, hey, yeah, there's some nutrition on board, then we can start our day.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

and have a really, really difficult time accessing any kind of parasympathetic responses down the way. Where if you have something really small where you're bringing blood sugar up, then it's signaling to the hypothalamus, hey, yeah, there's some nutrition on board, then we can start our day.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So again, it has to look at that circadian rhythm and those hormone fluxes, which people don't really either understand or talk about, because all of our hormones flux through the day. So you have to look at where's the peak of cortisol, how does estrogen flux, how does luteinizing hormone flux, progesterone, all of these things that have this tight interplay.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So again, it has to look at that circadian rhythm and those hormone fluxes, which people don't really either understand or talk about, because all of our hormones flux through the day. So you have to look at where's the peak of cortisol, how does estrogen flux, how does luteinizing hormone flux, progesterone, all of these things that have this tight interplay.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

So again, it has to look at that circadian rhythm and those hormone fluxes, which people don't really either understand or talk about, because all of our hormones flux through the day. So you have to look at where's the peak of cortisol, how does estrogen flux, how does luteinizing hormone flux, progesterone, all of these things that have this tight interplay.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And the more we're doing the hormone research and the more we're understanding these perturbations and how important it is to fuel for it to stay out of any kind of low energy availability stance.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And the more we're doing the hormone research and the more we're understanding these perturbations and how important it is to fuel for it to stay out of any kind of low energy availability stance.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And the more we're doing the hormone research and the more we're understanding these perturbations and how important it is to fuel for it to stay out of any kind of low energy availability stance.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Exactly.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Exactly.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Exactly.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And it gets worse as you get older. Because if we're seeing, as women are getting into perimenopause, which is in their 40s, and we have more fluctuation of those hormones and an increase in baseline cortisol anyway, then when you look at fasted training, it increases that cortisol drive and that sympathetic drive.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And it gets worse as you get older. Because if we're seeing, as women are getting into perimenopause, which is in their 40s, and we have more fluctuation of those hormones and an increase in baseline cortisol anyway, then when you look at fasted training, it increases that cortisol drive and that sympathetic drive.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And it gets worse as you get older. Because if we're seeing, as women are getting into perimenopause, which is in their 40s, and we have more fluctuation of those hormones and an increase in baseline cortisol anyway, then when you look at fasted training, it increases that cortisol drive and that sympathetic drive.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And because it's at a point where you really need to polarize your training to get any kind of body composition change, not having any fuel before high intensity workout puts them in moderate intensity. They just can't hit the intensities they need to. Same with resistance training. Like you go in and a lot of women are now working on sessional RPE or rating perceived exertion.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And because it's at a point where you really need to polarize your training to get any kind of body composition change, not having any fuel before high intensity workout puts them in moderate intensity. They just can't hit the intensities they need to. Same with resistance training. Like you go in and a lot of women are now working on sessional RPE or rating perceived exertion.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

And because it's at a point where you really need to polarize your training to get any kind of body composition change, not having any fuel before high intensity workout puts them in moderate intensity. They just can't hit the intensities they need to. Same with resistance training. Like you go in and a lot of women are now working on sessional RPE or rating perceived exertion.

Huberman Lab
Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

Or you go in and say, okay, we need you to hit an eight on the squat. So you have two reps in reserve and a sessional RPE of an eight. Well, if they're not fueled, then we're seeing trends that they're missing around two to 5% of that top load. So they're not really lifting in that zone that they need to be in.