Dr. Trisha Pasricha
speaker
2,195 appearances
5 recordings
5 series
first heard Mar 2026
last heard 8 Jul
Dr. Trisha Pasricha’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 5 in all, peaking in Apr 2026 with 2.
Appearances
Some people call the one in our guts the second brain.
That's not what I call it.
And they are evolutionarily very closely intertwined.
And one of the ways that they communicate is the vagus nerve.
And I know we'll talk a lot about that.
But remember that your gut does a lot more than just transport and magically transform food individually.
into waste, it is constantly producing neurotransmitters, the same neurotransmitters that the brain in your head produces, like dopamine, which is what I study in my lab, serotonin.
And it sends these signals up through the vagus nerve to the brain, and it's in the background, but it is constantly influencing our mood, our hormones, and probably most diseases in all of our body, our heart, our lungs, our brain, you can trace the origin to some extent to the
And there's an uncomfortable truth there too, which is that, you know, we can survive despite being brain dead, right?
Why?
How?
Well, it's because we have a functioning enteric nervous system.
As long as that is functioning and you still have some brainstem input with a breathing tube, you will survive because your enteric nervous system is still nourishing and feeding all of the other cells in your body.
That's how important it is.
Yeah, there's two main ways.
Most of how we've thought about the gut-brain connection, I think, has been in terms of how the brain communicates with the gut.
We live that experience.
every day right you know when you're going on a date you get butterflies in your stomach like flora mentioned or if you're nervous like suddenly you have to use the bathroom and it's your turn at karaoke and there's no bathroom in sight why and then when you sing your song suddenly you don't have to go anymore and some of the ways those types of communications happen some of it is hormone signaling some of that can happen through the bloodstream from the brain down to the gut
A lot of it happens through the vagus nerve.
The vagus nerve is this long cranial nerve.
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