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Dr. Trisha Pasricha

👤 Speaker
1766 total appearances

Appearances Over Time

Podcast Appearances

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

I really think that like sometimes when we're like just scraping our bums, a lot of people have sensitivity in that area.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

So people who have fissures, who have hemorrhoids, women who are postpartum, I tell all of my postpartum patients this, just a gentle dab is all you need.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

Yeah, there's two big ones for me.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

One is leaky gut.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

Leaky gut started as a very sound scientific phenomena in neurogastroenterology.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

This is what we study.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

What we study is increased intestinal permeability.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

And that's where this idea of leaky gut first started.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

So increased intestinal permeability is simply this.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

Our guts are aligned with these cells on the surface, and those cells are usually pretty tightly close together.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

But different things happen throughout the day that cause the junctions between those cells to just slightly open up.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

When they open up, other cells can travel through back and forth.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

Chemical signals can move.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

That's happening to all of us.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

We have increased intestinal permeability multiple times during the day.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

Stress can do it, what we eat can do it, infections can do it.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

This is happening all the time.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

There are very few known from start to finish situations where we can, at this point, conclusively say part of the problem and the mechanism was the increased intestinal permeability in this medical condition.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

So for example, one of those is liver fibrosis, liver disease.

The Mel Robbins Podcast
The Gut Health Episode: Harvard Doctor Reveals What’s Normal (and What’s Not)

alcohol increases intestinal permeability, and then those chemicals and toxins hit your liver and cause damage.