Dr. Will Bulsiewicz

Yeah, so we're in perpetual survival mode and constantly activating it. And there's so many things. I mean, anything that's getting your heart rate up and your blood pressure up, it could be something so silly and inconsequential as what's happening on Twitter. But you have a fight with a partner. this is going to activate your sympathetic nervous system.

And so what I'm about to describe applies to anything where it's activating your sympathetic nervous system, whether it's a fight with a partner or something else. Your brain releases a hormone called CRH or corticotropin-releasing hormone. And this CRH will spread through the body. And in the process of doing this is basically activating this adrenaline response.

And so what I'm about to describe applies to anything where it's activating your sympathetic nervous system, whether it's a fight with a partner or something else. Your brain releases a hormone called CRH or corticotropin-releasing hormone. And this CRH will spread through the body. And in the process of doing this is basically activating this adrenaline response.

And so what I'm about to describe applies to anything where it's activating your sympathetic nervous system, whether it's a fight with a partner or something else. Your brain releases a hormone called CRH or corticotropin-releasing hormone. And this CRH will spread through the body. And in the process of doing this is basically activating this adrenaline response.

And that includes literally in the adrenal glands and the release of epinephrine, norepinephrine. So, but there's consequences. to the release of CRH. And particularly the place where we pay the price is within our gut because it basically will break down the gut barrier, lead to the release of a toxin called lipopolysaccharide into the bloodstream and inflict harm on the gut microbes.

And that includes literally in the adrenal glands and the release of epinephrine, norepinephrine. So, but there's consequences. to the release of CRH. And particularly the place where we pay the price is within our gut because it basically will break down the gut barrier, lead to the release of a toxin called lipopolysaccharide into the bloodstream and inflict harm on the gut microbes.

And that includes literally in the adrenal glands and the release of epinephrine, norepinephrine. So, but there's consequences. to the release of CRH. And particularly the place where we pay the price is within our gut because it basically will break down the gut barrier, lead to the release of a toxin called lipopolysaccharide into the bloodstream and inflict harm on the gut microbes.

And this is the reason why I think that Everyone can sort of relate to this in their own way. You know, imagine a stressful event. Where do you manifest that physically? Some people, it's a migraine headache, which by the way is also connected to the gut. But for many people, it's in the gut. It's here. And it could be a small little thing, like you feel it.

And this is the reason why I think that Everyone can sort of relate to this in their own way. You know, imagine a stressful event. Where do you manifest that physically? Some people, it's a migraine headache, which by the way is also connected to the gut. But for many people, it's in the gut. It's here. And it could be a small little thing, like you feel it.

And this is the reason why I think that Everyone can sort of relate to this in their own way. You know, imagine a stressful event. Where do you manifest that physically? Some people, it's a migraine headache, which by the way is also connected to the gut. But for many people, it's in the gut. It's here. And it could be a small little thing, like you feel it.

It could turn into nausea or it can grow into waves of cramping pain that fold you over. And what is happening there is the physiologic consequence of sympathetic overdrive and this CRH release. So when I was in medical school, I remember like on big test days, we were in such a pressure cooker.

It could turn into nausea or it can grow into waves of cramping pain that fold you over. And what is happening there is the physiologic consequence of sympathetic overdrive and this CRH release. So when I was in medical school, I remember like on big test days, we were in such a pressure cooker.

It could turn into nausea or it can grow into waves of cramping pain that fold you over. And what is happening there is the physiologic consequence of sympathetic overdrive and this CRH release. So when I was in medical school, I remember like on big test days, we were in such a pressure cooker.

And I remember on big test days, like literally there was a line out the bathroom door because everyone's gut was upset. Everyone had diarrhea.

And I remember on big test days, like literally there was a line out the bathroom door because everyone's gut was upset. Everyone had diarrhea.

And I remember on big test days, like literally there was a line out the bathroom door because everyone's gut was upset. Everyone had diarrhea.

Yeah, there's consequences to all choices that exist in nature, right? So This is us activating the part of our body that is needed for survival in that moment. So what we get is we get, you know, enhanced ability to focus and we get release of blood sugar into our bloodstream, which powers our muscles, allows us to run faster and, you know, things of that, like more of a physical nature.

Yeah, there's consequences to all choices that exist in nature, right? So This is us activating the part of our body that is needed for survival in that moment. So what we get is we get, you know, enhanced ability to focus and we get release of blood sugar into our bloodstream, which powers our muscles, allows us to run faster and, you know, things of that, like more of a physical nature.

Yeah, there's consequences to all choices that exist in nature, right? So This is us activating the part of our body that is needed for survival in that moment. So what we get is we get, you know, enhanced ability to focus and we get release of blood sugar into our bloodstream, which powers our muscles, allows us to run faster and, you know, things of that, like more of a physical nature.

But the problem is like, That's not what we need in the current 21st century to deal with a lot of the issues that we run into. So it's sort of a misplaced physiologic benefit And again, there's always going to be some sort of price that you have to pay.