Dr. Will Cole
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Podcast Appearances
are passing through the gut lining because there's these proteins that govern gut lining permeability called occludin and zonulin. Think of the Z in zonulin, this protein that protects the gut lining, the tight junctions of the gut as a zipper. So this increased zonulin antibody activity, increased zonulin activity, You're going to have things breached, getting from the gut into the bloodstream.
are passing through the gut lining because there's these proteins that govern gut lining permeability called occludin and zonulin. Think of the Z in zonulin, this protein that protects the gut lining, the tight junctions of the gut as a zipper. So this increased zonulin antibody activity, increased zonulin activity, You're going to have things breached, getting from the gut into the bloodstream.
And that is at least part of it that researchers have looked at for the past 15 or 20 years or so as this event of what's happening as to why this molecular mimicry is happening. Because the immune system sees undigested food proteins, sees bacterial toxins and says, what the heck? It's not actually saying what the heck, but I'm speaking for your immune system right now.
And that is at least part of it that researchers have looked at for the past 15 or 20 years or so as this event of what's happening as to why this molecular mimicry is happening. Because the immune system sees undigested food proteins, sees bacterial toxins and says, what the heck? It's not actually saying what the heck, but I'm speaking for your immune system right now.
And that is at least part of it that researchers have looked at for the past 15 or 20 years or so as this event of what's happening as to why this molecular mimicry is happening. Because the immune system sees undigested food proteins, sees bacterial toxins and says, what the heck? It's not actually saying what the heck, but I'm speaking for your immune system right now.
And it is tagging the undigested food proteins with that flag for destruction, the antibody, and then cross-reacts because it's similar enough in structure, the thyroid is similar enough in structure that it's attacking the thyroid, but then it could be the joints, the gut, the brain, or anything. Right. So we have to look at what's destroying that gut lining. Yeah.
And it is tagging the undigested food proteins with that flag for destruction, the antibody, and then cross-reacts because it's similar enough in structure, the thyroid is similar enough in structure that it's attacking the thyroid, but then it could be the joints, the gut, the brain, or anything. Right. So we have to look at what's destroying that gut lining. Yeah.
And it is tagging the undigested food proteins with that flag for destruction, the antibody, and then cross-reacts because it's similar enough in structure, the thyroid is similar enough in structure that it's attacking the thyroid, but then it could be the joints, the gut, the brain, or anything. Right. So we have to look at what's destroying that gut lining. Yeah.
And these environmental toxins like glyphosate. Oh, yeah. You talk about herbicides and pesticides, what it's doing to decimate this gut garden.
And these environmental toxins like glyphosate. Oh, yeah. You talk about herbicides and pesticides, what it's doing to decimate this gut garden.
And these environmental toxins like glyphosate. Oh, yeah. You talk about herbicides and pesticides, what it's doing to decimate this gut garden.
Yeah.
Yeah.
Yeah.
The gut microbiome, big part, microplastics. They're finding it 90% of human tissue. Yeah. There's not a healthy amount of microplastics in the human body. Right. We should not be like microdosing microplastics. But we are doing more than microdosing these microplastics.
The gut microbiome, big part, microplastics. They're finding it 90% of human tissue. Yeah. There's not a healthy amount of microplastics in the human body. Right. We should not be like microdosing microplastics. But we are doing more than microdosing these microplastics.
The gut microbiome, big part, microplastics. They're finding it 90% of human tissue. Yeah. There's not a healthy amount of microplastics in the human body. Right. We should not be like microdosing microplastics. But we are doing more than microdosing these microplastics.
Yeah, so the first part of the question, you said, how do they find out? If we're looking, and this is a oversimplified Venn diagram, but when we started the conversation with these people that don't necessarily have high, these conventional inflammation markers like HSCRP, they don't have maybe super high homocysteine, their metabolic labs look pretty normal.
Yeah, so the first part of the question, you said, how do they find out? If we're looking, and this is a oversimplified Venn diagram, but when we started the conversation with these people that don't necessarily have high, these conventional inflammation markers like HSCRP, they don't have maybe super high homocysteine, their metabolic labs look pretty normal.
Yeah, so the first part of the question, you said, how do they find out? If we're looking, and this is a oversimplified Venn diagram, but when we started the conversation with these people that don't necessarily have high, these conventional inflammation markers like HSCRP, they don't have maybe super high homocysteine, their metabolic labs look pretty normal.