Elena Resnick
speaker
130 appearances
2 recordings
1 series
first heard Jan 2025
last heard 17 Jul
Elena Resnick’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
IgE is immunoglobulin E. It's an immunoglobulin that's made by B cells.
It probably had more of a function evolutionarily in terms of fighting off parasitic disease, etc.
It certainly was not evolutionarily made to react to peanuts and pollens, but we don't know why in some people those types of antibodies are made that are specific against harmless substances.
It's the most serious type of IgE-mediated allergic reaction where the allergy cells explode, they release all sorts of mediators, histamines, tryptase, etc., and that causes your vessels to vasodilate.
Fluid runs in, people get hives, people get swelling, people's throat closes up, or you have difficulty breathing.
Your airways constrict.
And because the vessels all over the body are dilating, your blood pressure drops.
You can't get blood back up to your heart and you have a cardiac arrest.
The studies show that 90 percent of people who believe that they are allergic to penicillin actually can tolerate it.
Oh, my gosh.
I don't know that I can think of any.
I think that the vast majority of people either have or were told that they had some sort of reaction in childhood.
So that is the most common history.
I think you are 100% wrong, I'm sorry to say.
The other drugs, we're so lucky to have them, but many of them have much more severe side effect profiles than penicillin does.
They can have more serious complications.
They're much more expensive.
And in certain cases, for example, vancomycin, they can actually increase the risk of drug-resistant bacteria.
How do we do that?
So every good experiment has a control.
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