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Elena Resnick

👤 Person
75 total appearances

Appearances Over Time

Podcast Appearances

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

It probably had more of a function evolutionarily in terms of fighting off parasitic disease, etc., It certainly was not evolutionarily made to react to peanuts and pollens, but we don't know why in some people those types of antibodies are made that are specific against harmless substances.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

It's the most serious type of IgE-mediated allergic reaction where the allergy cells explode, they release all sorts of mediators, histamines, tryptase, etc., and that causes your vessels to vasodilate. Fluid runs in, people get hives, people get swelling, people's throat closes up, or you have difficulty breathing.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

It's the most serious type of IgE-mediated allergic reaction where the allergy cells explode, they release all sorts of mediators, histamines, tryptase, etc., and that causes your vessels to vasodilate. Fluid runs in, people get hives, people get swelling, people's throat closes up, or you have difficulty breathing.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

It's the most serious type of IgE-mediated allergic reaction where the allergy cells explode, they release all sorts of mediators, histamines, tryptase, etc., and that causes your vessels to vasodilate. Fluid runs in, people get hives, people get swelling, people's throat closes up, or you have difficulty breathing.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Your airways constrict. And because the vessels all over the body are dilating, your blood pressure drops. You can't get blood back up to your heart and you have a cardiac arrest.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Your airways constrict. And because the vessels all over the body are dilating, your blood pressure drops. You can't get blood back up to your heart and you have a cardiac arrest.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Your airways constrict. And because the vessels all over the body are dilating, your blood pressure drops. You can't get blood back up to your heart and you have a cardiac arrest.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

The studies show that 90 percent of people who believe that they are allergic to penicillin actually can tolerate it.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

The studies show that 90 percent of people who believe that they are allergic to penicillin actually can tolerate it.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

The studies show that 90 percent of people who believe that they are allergic to penicillin actually can tolerate it.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Oh, my gosh. I don't know that I can think of any. I think that the vast majority of people either have or were told that they had some sort of reaction in childhood. So that is the most common history.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Oh, my gosh. I don't know that I can think of any. I think that the vast majority of people either have or were told that they had some sort of reaction in childhood. So that is the most common history.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

Oh, my gosh. I don't know that I can think of any. I think that the vast majority of people either have or were told that they had some sort of reaction in childhood. So that is the most common history.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

I think you are 100% wrong, I'm sorry to say. The other drugs, we're so lucky to have them, but many of them have much more severe side effect profiles than penicillin does. They can have more serious complications. They're much more expensive. And in certain cases, for example, vancomycin, they can actually increase the risk of drug-resistant bacteria.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

I think you are 100% wrong, I'm sorry to say. The other drugs, we're so lucky to have them, but many of them have much more severe side effect profiles than penicillin does. They can have more serious complications. They're much more expensive. And in certain cases, for example, vancomycin, they can actually increase the risk of drug-resistant bacteria.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

I think you are 100% wrong, I'm sorry to say. The other drugs, we're so lucky to have them, but many of them have much more severe side effect profiles than penicillin does. They can have more serious complications. They're much more expensive. And in certain cases, for example, vancomycin, they can actually increase the risk of drug-resistant bacteria.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

How do we do that? So every good experiment has a control. And the controls that we use are saline, which is salt water. Nobody is allergic to that. And histamine, which is the body's allergic chemical. So we prick you. And when I say prick, I mean we clean off the forearm. And then we use tiny needles to introduce just under the surface of the skin saline, histamine, and our penicillin reagents.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

How do we do that? So every good experiment has a control. And the controls that we use are saline, which is salt water. Nobody is allergic to that. And histamine, which is the body's allergic chemical. So we prick you. And when I say prick, I mean we clean off the forearm. And then we use tiny needles to introduce just under the surface of the skin saline, histamine, and our penicillin reagents.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

How do we do that? So every good experiment has a control. And the controls that we use are saline, which is salt water. Nobody is allergic to that. And histamine, which is the body's allergic chemical. So we prick you. And when I say prick, I mean we clean off the forearm. And then we use tiny needles to introduce just under the surface of the skin saline, histamine, and our penicillin reagents.

Freakonomics Radio
617. Are You Really Allergic to Penicillin?

So it's four small pricks under the surface of the skin.