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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

One thing I thought was fascinating in the paper in Cell, you wrote, for instance, the short read archive of biological sequence data holds over 14 petabytes of information, which is 1,000 times larger than the data set used to train chat GPT.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

I mean, that's a lot of tokens.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

That's a lot of stuff.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Compute resources.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's almost like you're going to need a deep-seek algorithm

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

type of way to get this, I mean, not that deep-seek is as it's claimed to be so much more economical, but there's a data challenge here in terms of working with that massive amount that is different than the language of human language, that is, our language, wouldn't you say?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Yeah.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Well, there's two, I think, phenomenal figures in your cell paper.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

The first one that takes across the capabilities of the virtual cell and the second that compares the virtual cell to the real or the physical cell.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And we'll link that with this in the transcript.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And the other thing we'll link is that there's a nice Atlantic article.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

A virtual cell is a

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

is a holy grail of science.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's getting closer.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

That may not be quite close as like next week or year, but it's getting close.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

And that's good for people who are not well grounded in this because it's much more taken out of the technical realm.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

This is really exciting, what you're onto here.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

What's interesting, Steve, since I've known you for so many years, earlier in your career, you really worked on omics, that is DNA and RNA.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

In recent times, you've made this switch to cells.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Is that just because you're trying to anticipate the field?