Eric Topol

I don't know how you figured this out.

Just telling a lie would get your digestive tract into high gear.

Maybe you could amplify that.

Well, I just think the emphasis, which is in a whole other section in the book, the science here, is fantastic because the gut-brain bidirectional interactions are extraordinary.

You touch on a few, the vagal nerve,

the corticotropin release factor, the stress fear, cephalic phase of digestion.

One thing that's very dear to me is the, what you call the TRPV1 receptor, but the piezoreceptor, my colleague, my very close friend,

Artem Padapushin got the Nobel Prize for that back in 2021.

And that's everything.

And like when you have that urge, that's the piezo 2 receptor or connected to the TRPV1.

So this is, you know, mass cell activation, the microbiome.

You cover the science here explicitly.

So this is not just a book that is about, you know,

how to make a better bowel movement and have joy and how to have Cinderella moments, it also gets into the science.

But a lot of the practical things, if you can touch on here with me, Trisha,

You did touch on alcohol and NSAIDs, non-steroidal and anti-inflammatory.

So what's the take on each of those?

No, it's great.

And again, there's a whole chapter on women and the whole issues that surround the GI and poops and the whole works.

Now, you mentioned social media and all the predators out there.